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Tacrolimus concentration in blood (2-hour post-dose)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of tacrolimus, a medication used to prevent organ rejection after a transplant, in your blood 2 hours after you took your dose. It helps doctors check if your dose is working properly.

Quick summary

["This test helps ensure your transplant medication is at the right level for safety and effectiveness."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
92729-3
Short code
Tacrolimus 2h p Bld-mCnc
Synonyms
Tacrolimus 2h p Bld-mCnc
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order this test if you’re taking tacrolimus to manage organ rejection after a transplant. It helps monitor whether your medication is keeping your immune system from attacking your new organ. This test is especially important if you’re on a strict dosing schedule or if your levels might fluctuate due to other health conditions.

What Does This Test Tell You?

The result tells your healthcare team how much tacrolimus is in your blood at a specific time. Low levels might mean your dose isn’t working well, while high levels could increase your risk of side effects. Your doctor will use these results to adjust your medication if needed.

How Is This Test Performed?

A small blood sample is taken from a vein, usually in your arm. The sample is then sent to a lab for analysis using a specialized method to measure tacrolimus levels accurately.

What Do My Results Mean?

Your results will be compared to guidelines specific to your situation (like transplant type, other medications, or health status). Your doctor will explain what the numbers mean in the context of your care plan.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test is critical for transplant patients because tacrolimus levels must be carefully balanced. Too little can lead to organ rejection, while too much can cause serious side effects like kidney damage or infections. Regular monitoring helps prevent these risks and ensures your treatment stays effective.

Short name

Tacrolimus 2-hour blood level

Frequently asked questions

Why do I need this test every few weeks?
Your tacrolimus levels can change over time due to factors like diet, illness, or other medications. Regular testing helps your doctor adjust your dose to keep your levels safe and effective without causing side effects.
What if my results are too high or too low?
If your levels are too high, your doctor may reduce your dose or temporarily stop it to lower your risk of side effects. If levels are too low, they might increase your dose or add another medication to help maintain the right balance.
Can I eat or drink before this test?
You should follow your doctor’s instructions, but generally, you may eat and drink normally unless they specify otherwise. Some medications (like grapefruit products) can affect tacrolimus levels, so check with your healthcare team.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy