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Tacrolimus concentration in whole blood

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of tacrolimus, a medication used to prevent organ rejection after a transplant, in your blood. It helps doctors monitor your dose to ensure it stays within safe levels.

Quick summary

["Tacrolimus levels help prevent overdose or underdose, which can affect your health after a transplant."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
92727-7
Short code
Tacrolimus Bld-AUC
Synonyms
Tacrolimus Bld-AUC
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order this test if you’re taking tacrolimus to manage an organ transplant or another condition where this medication is prescribed. Regular monitoring helps adjust your dose to keep it effective while minimizing side effects.

What to Expect Before the Test

No special preparation is needed. You may have a small needle inserted into your arm or hand to draw blood. The process usually takes a few minutes, and you can resume normal activities afterward.

What the Results Mean

Results help your healthcare team determine if your dose is correct. Very high or low levels can signal the need for adjustments. Your doctor will discuss these findings with you.

Common Reasons for Testing

Doctors check tacrolimus levels to ensure it’s working properly, especially if you experience side effects like nausea, tremors, or unusual fatigue. It’s also done during transplant follow-up to prevent rejection.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Tacrolimus Blood Level

Frequently asked questions

Why might my tacrolimus level be checked more often?
Your doctor may check levels more frequently if you’re taking other medications that interact with tacrolimus, have changes in kidney function, or experience symptoms like nausea, dizziness, or vision changes.
What should I do if my tacrolimus level is too high or too low?
Your doctor will adjust your medication dose based on the results. They may also recommend lifestyle changes, such as avoiding grapefruit products, which can affect how your body processes the drug.
Can I drink alcohol before this test?
Alcohol may not interfere with the test itself, but it can affect how your body processes tacrolimus. Always follow your doctor’s advice about alcohol consumption while on this medication.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy