Total Antioxidant Capacity of Serum (or Plasma)

What This Test Measures

Antioxidants in your blood work by donating electrons to free radicals, preventing them from causing damage to cells. This test quantifies the overall capacity of your serum or plasma to perform this protective function, often reflecting the combined activity of multiple antioxidants like vitamins C and E, glutathione, and others.

Why It Matters in Health

High antioxidant capacity may indicate strong natural defenses against oxidative stress, which is linked to aging, inflammation, and chronic diseases. Low levels could suggest increased vulnerability to oxidative damage, potentially contributing to conditions like cardiovascular disease or certain cancers.

Common Causes of Variations

Factors that might influence antioxidant capacity include diet (e.g., intake of fruits, vegetables, and healthy fats), lifestyle (e.g., smoking, alcohol use), chronic illnesses, and certain medications. Stress, poor sleep, or infections may also temporarily affect these levels.

What to Expect During the Test

You’ll have a small blood sample drawn from your arm, similar to other routine blood tests. The sample is then analyzed in a lab to determine its antioxidant capacity. Results are typically reported as a measure of total antioxidant capacity, though exact reference ranges vary by lab.