Total Antioxidant Capacity (Serum or Plasma)

What Does This Test Measure?

Total antioxidant capacity reflects the combined activity of various antioxidants in your blood, such as vitamins (like vitamin C and E), glutathione, and other compounds that help prevent cellular damage caused by unstable molecules called free radicals.

Why Might You Need This Test?

Your doctor may order this test if you have symptoms of oxidative stress, such as chronic fatigue, skin issues, or conditions linked to oxidative damage (e.g., certain cancers, cardiovascular disease, or autoimmune disorders). It can also be part of broader health evaluations, especially in patients with known antioxidant deficiencies or exposure to environmental toxins.

Common Reasons for Testing

This test is sometimes used in research or specialized clinical settings to monitor antioxidant status in conditions where oxidative stress is suspected, though it’s not routinely part of standard preventive care.

What to Expect Before the Test

No special preparation is usually needed. You may provide a blood sample (serum or plasma) or, less commonly, a urine sample, depending on the lab’s protocol. Avoid alcohol for 24 hours before testing if instructed, as it may affect results.