Full-length genetic sequencing of full-length mutations in the *TAT* (Thrombin) gene from whole blood DNA
This test checks for specific changes (mutations) in the gene that codes for thrombin, a protein involved in blood clotting. Mutations here may affect how well your blood clots normally.
["This test helps diagnose or monitor conditions linked to abnormal thrombin function."]
Key facts at a glance
- LOINC
- 77063-6
- Short code
- TAT Full Mut Anl Bld/T Seq
- Synonyms
- TAT Full Mut Anl Bld/T Seq
- Category
- chemistry
- Sample
- whole-blood
- Container
- Lavender-top (EDTA)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- sequencing
- Specimen volume
- 3 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
Why This Test Might Be Ordered
Your healthcare provider may recommend this test if you have symptoms or a family history suggesting bleeding disorders, clotting issues, or conditions like thrombotic thrombocytopenic purpura (TTP) or hereditary thrombophilia. It could also be used if you’ve had unexplained bleeding or clotting events.
What to Expect Before the Test
No special preparation is needed. You’ll provide a small blood sample, usually drawn from your arm. The sample is then sent to a lab for genetic analysis.
What the Test Results Mean
Results will identify whether specific mutations in the thrombin gene are present. These mutations can sometimes be inherited or acquired. Your provider will discuss findings in relation to your symptoms and medical history.
Common Conditions Linked to This Test
Mutations in the thrombin gene may be associated with rare bleeding disorders or inherited clotting risks. Some mutations could also be linked to conditions affecting blood vessel function or platelet activity.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical significance: This test is critical for diagnosing inherited or acquired disorders affecting thrombin activity, which can influence bleeding tendencies or clotting risks. Early detection may guide treatment or preventive strategies.
Short name
Thrombin Gene Mutation Sequencing (blood)
Frequently asked questions
What does a positive result mean?
How often should I get this test?
Can lifestyle changes help if I have a mutation?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy