Tbevigmtitrcsfia
This test detects IgM antibodies against tick-borne encephalitis virus in cerebrospinal fluid to help diagnose viral infection affecting the brain and spinal cord.
{"Detects IgM antibodies in cerebrospinal fluid indicating recent infection","Helps diagnose tick-borne encephalitis, a viral brain infection","Sample is collected via lumbar puncture (spinal tap)","Positive result suggests current or recent TBEV infection","Transmitted through tick bites, common in parts of Europe and Asia"}
Key facts at a glance
- LOINC
- 104397-5
- Short code
- TBEV IgM CSF
- Synonyms
- TBEV IgM Titr CSF IA
- Category
- cardiac
- Sample
- csf
- Container
- Sterile CSF collection container (polypropylene or glass tube)
- Units
- N/A
- Ref low
- 0
- Ref high
- 10
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 0–120 years
- Method
- Immunoassay
- CPT
- 86635
- SNOMED
- 122442009
- Specimen volume
- 1-2 mL of cerebrospinal fluid
- Stability
- Refrigerated (2-8°C): up to 72 hours. Frozen (-20°C or below): up to 30 days. Avoid repeated freeze-thaw cycles.
- Hemolysis max
- 200
- TAT
- 24–72 hours
- Order
- routine
What is this test?
The European tick-borne encephalitis virus IgM antibody test is a laboratory test performed on cerebrospinal fluid (CSF), the clear fluid surrounding your brain and spinal cord. It detects IgM antibodies that your immune system produces in response to the tick-borne encephalitis virus (TBEV). This test uses immunoassay techniques to identify whether these specific antibodies are present, helping doctors determine if you have a current or recent infection affecting your central nervous system.
How is the sample collected?
Cerebrospinal fluid is collected through a procedure called a lumbar puncture, commonly known as a spinal tap. During this procedure, a healthcare provider inserts a thin needle between the bones (vertebrae) in your lower back to withdraw a small amount of CSF. The fluid is then sent to a laboratory for analysis. This method allows direct detection of antibodies in the fluid that surrounds the brain and spinal cord, which is particularly important for diagnosing neurological infections.
Why might I need this test?
Your doctor may order this test if you have symptoms of tick-borne encephalitis, especially if you have been in areas where TBE is common (such as parts of Central, Eastern, and Northern Europe and northern Asia). Symptoms typically include fever, headache, fatigue, muscle aches, and in more severe cases, meningitis (inflammation of the membranes surrounding the brain) or encephalitis (inflammation of the brain). The test is particularly important when symptoms suggest the infection has spread to the central nervous system.
Reference range
Negative: < 1:10 titer or No detectable IgM antibodies detected. Positive: >= 1:10 titer or Detectable IgM antibodies (indicates acute or recent infection). Borderline: 1:5 to 1:10 titer (recommend repeat testing)N/A
No special preparation required. Patient should inform healthcare provider of any recent infections, tick bites, or travel to endemic areas. Standard CSF collection procedure applies.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Frequently asked questions
Is tick-borne encephalitis the same as Lyme disease?
How long does it take to get results?
Can the test be done on blood instead of CSF?
Is vaccination available for tick-borne encephalitis?
Sources
- 1
- 2
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy