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Total Serum Immunoglobulin G (IgG) Level

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of Immunoglobulin G (IgG), a type of antibody in your blood. IgG helps protect your body from infections and is important for long-term immunity.

Quick summary

["IgG helps fight infections and supports immune function by identifying and neutralizing harmful substances."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
110124-5
Short code
T canis IgM Msmt Ser
Synonyms
T canis IgM Msmt Ser
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What IgG Does in Your Body

IgG is the most common type of antibody in your blood. It plays a key role in defending against bacteria and viruses, helping your immune system remember past infections to provide faster protection if you encounter the same pathogen again. It also helps neutralize toxins and foreign substances, contributing to overall immune defense.

Why Your Doctor Might Order This Test

Your doctor may order an IgG test to check for immune system function, diagnose conditions like immunodeficiency, or monitor treatment responses in diseases such as HIV, lupus, or certain autoimmune disorders. It can also help evaluate immune responses in newborns or individuals with chronic infections.

When You Might Need This Test

You might need this test if you have symptoms like frequent infections, unexplained fatigue, recurrent ear or sinus infections, or if you’re being treated for an immune-related condition. Doctors may also order it as part of a routine checkup for certain high-risk groups, such as newborns or individuals with weakened immune systems.

What to Expect During the Test

A simple blood draw is used to collect a serum sample. You’ll lie down or sit comfortably while a healthcare professional inserts a small needle into your arm. The blood is then sent to a lab for analysis. The process usually takes a few minutes, and you may feel slight discomfort or bruising afterward.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance of IgG Levels

Short name

IgG Level

Frequently asked questions

How long does it take to get the results of this test?
Results are typically available within 1 to 3 business days, depending on your lab’s processing schedule. Your healthcare provider will discuss the results with you during your follow-up visit.
What do low IgG levels mean?
Low IgG levels may indicate a weakened immune system, which can increase your risk of infections. This could be due to conditions like primary immunodeficiency, chronic liver disease, or certain medications that affect immunity. Your doctor may recommend further testing or treatments to address the underlying cause.
Can high IgG levels be harmful?
High IgG levels alone are usually not harmful, but they can sometimes indicate chronic infections, autoimmune diseases, or other conditions like multiple myeloma. Your doctor will consider the context of your symptoms and other test results to determine if further evaluation is needed.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy