T-cell subset quantification by flow cytometry (serum/plasma donor-derived lymphocyte fraction)
This test measures different types of T-cells (a type of white blood cell) in a sample of your blood. It helps doctors understand your immune system’s balance and identify potential immune disorders.
["Assessing immune health and detecting immune-related conditions through T-cell profiling."]
Key facts at a glance
- LOINC
- 96047-6
- Short code
- T Cell XM Pt ser+Don bld Ql FC
- Synonyms
- T Cell XM Pt ser+Don bld Ql FC
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 0.8
- Ref high
- 1.2
- Critical range
- — – 5 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- flow-cytometry
- CPT
- 85610
- SNOMED
- 396252006
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
The test evaluates specific populations of T-cells, including helper T-cells, cytotoxic T-cells, regulatory T-cells, and memory T-cells. These cells play critical roles in immune responses, helping your body fight infections and maintain immune balance.
Why It Might Be Ordered
Your doctor may recommend this test if you have symptoms like frequent infections, autoimmune conditions (e.g., rheumatoid arthritis, lupus), or if you’re undergoing treatment for cancer or immune disorders. It can also help monitor immune function before or after treatments like chemotherapy or stem cell transplants.
Sample and Preparation
A small blood sample is drawn from your arm. The blood is processed to separate white blood cells, which are then analyzed using a specialized flow cytometry technique. No special preparation is needed, but fasting may not be required unless specified by your doctor.
What to Expect During the Test
The blood draw takes about 5 minutes. Afterward, you may feel a slight pinch or bruise at the site. The lab processes the sample within hours, and results are typically available within a few days. No follow-up action is needed unless your doctor requests further testing.
Reference range
INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A
Inform your healthcare provider if you are taking blood thinners. No special preparation required.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Abnormal T-cell counts can indicate immune deficiencies (e.g., HIV/AIDS), overactive immune responses (e.g., in autoimmune diseases), or immune system dysregulation. For example, low helper T-cells may suggest weakened immune function, while high regulatory T-cells could signal autoimmune activity. This test helps guide treatment decisions and monitor immune health over time.
Short name
T-cell subset analysis
Frequently asked questions
Will I need to prepare for this test?
How long will I wait for results?
Can this test detect infections like COVID-19?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy