Lymphocyte Subset Counts by Tissue Type (Tissue-Specific Lymphocyte Profile)
This test measures the number of lymphocytes (a type of white blood cell) in different tissues, including lymph nodes and tissue samples, to help assess immune function and potential infections or inflammatory conditions.
Assists in diagnosing immune disorders, infections, or cancer by evaluating lymphocyte distribution across tissues.
Key facts at a glance
- LOINC
- 105303-2
- Short code
- TC+Mcrphg+Lymphcyt PDL1/TC tiss
- Synonyms
- TC+Mcrphg+Lymphcyt PDL1/TC tiss
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 0
- Ref high
- 3
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- immune-stain
- CPT
- 86140
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Is Done
Your doctor may order this test if they suspect an immune-related condition, such as chronic infections, autoimmune diseases, or certain cancers. It can also help monitor treatment responses in patients with conditions affecting lymphocyte counts.
What to Expect Before the Test
No special preparation is typically needed. If a tissue sample is taken (e.g., biopsy), follow your healthcare provider’s instructions for fasting or avoiding certain medications. Blood tests may require fasting or avoiding certain foods/drugs for 12 hours beforehand.
Sample Collection Process
Blood samples are drawn from a vein in your arm, while tissue samples may be obtained through a biopsy (small sample from affected tissue). Results are analyzed using advanced techniques like electrophoresis or immunoassay to count lymphocyte subtypes.
What the Results Mean
Results show absolute counts of different lymphocyte types (e.g., B cells, T cells, natural killer cells) in blood or tissue. Abnormal counts may indicate immune suppression, overactivity, or tissue-specific immune responses.
Reference range
Normal: <3.0 mg/LN/A
No special preparation required. CRP may be affected by acute illness.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance: This test helps identify immune system imbalances, guide treatment for infections, autoimmune diseases, or cancers (e.g., lymphoma), and monitor immune recovery post-treatment. Low counts may signal immunodeficiency; high counts may suggest chronic inflammation or overactive immune responses.
Short name
Lymphocyte Profile by Tissue
Frequently asked questions
What causes abnormal lymphocyte counts in this test?
How long does it take to get results?
Can lifestyle changes affect this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy