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Tetradecanedioate/Creatinine, Urine — Ratio

Published: August 9, 2026Updated: August 16, 2026

A urine test that measures tetradecanedioate relative to creatinine, helping evaluate organic acid excretion and possible fatty acid metabolism problems.

Quick summary

["This ratio can help identify increased urinary excretion of tetradecanedioate, a substance that may be associated with fatty acid metabolism disorders."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
50061-1
Short code
Tdecanedioate/Creat Ur-sRto
Synonyms
Tdecanedioate/Creat Ur-sRto
Category
kidney
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

This test measures tetradecanedioate, also called tetradecanedioic acid, in urine relative to the amount of creatinine in the same sample. Creatinine is used to help account for differences in urine concentration.

Why might I need this test?

This specialized urine test may be ordered to investigate suspected fatty acid metabolism disorders or unusual organic acid excretion. It is usually interpreted along with symptoms, other laboratory results, and sometimes additional urine or blood tests.

How is the test performed?

A urine specimen is collected according to the laboratory's instructions and analyzed for tetradecanedioate and creatinine. The laboratory then calculates the tetradecanedioate-to-creatinine ratio. Depending on the order, a single urine sample or a timed collection may be required.

How do I prepare for the test?

Follow the collection instructions provided by your healthcare professional, including whether a spot urine or timed collection is needed. Unless specifically instructed otherwise, do not fast, change your diet, or stop prescribed medicines before collecting the sample.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Urine tetradecanedioate/creatinine ratio

Frequently asked questions

What does the tetradecanedioate-to-creatinine ratio show?
It shows the amount of tetradecanedioate in urine compared with creatinine. Using creatinine helps adjust for how concentrated or dilute the urine sample is.
Does an elevated result mean I have a fatty acid metabolism disorder?
No. An elevated result can suggest increased excretion of this substance, but it may have other causes and must be interpreted with symptoms and additional laboratory tests.
How is the urine sample collected?
Urine is collected in the container supplied by the laboratory, following any instructions for a spot sample or timed collection. The sample should be labeled and returned as directed.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy