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Carnitine Acylcarnitine Profile (Serum)

Published: August 9, 2026Updated: August 16, 2026

This test measures various fatty acid–carnitine compounds in your blood, which help assess how well your body converts fats for energy and detect potential metabolic disorders.

Quick summary

["Helps identify fatty acid metabolism issues or inherited disorders like mitochondrial diseases."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
53193-9
Short code
Tdecenoylcarn/C2 DBS-sRto
Synonyms
Tdecenoylcarn/C2 DBS-sRto
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The panel typically includes short-, medium-, and long-chain acylcarnitines (e.g., C2–C18), reflecting different stages of fat breakdown. Elevated levels of specific acylcarnitines may signal blockages or enzyme deficiencies in fatty acid oxidation.

Why It’s Ordered

Your doctor may request this test if you have symptoms like muscle weakness, fatigue, vomiting, or unexplained metabolic issues, especially in infants or those with a family history of metabolic disorders.

Common Conditions Linked to Results

Abnormal results may point to conditions such as carnitine palmitoyltransferase (CPT) deficiency, medium-chain acyl-CoA dehydrogenase (MCAD) deficiency, or other inherited disorders affecting fat metabolism.

Sample Collection & Preparation

A blood sample is drawn from a vein, usually in the arm. The sample is processed to separate serum (liquid part of blood) for analysis. Avoid fasting unless instructed, as diet can temporarily alter results.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Carnitine acylcarnitine panel

Frequently asked questions

What might cause elevated or low acylcarnitine levels?
Elevated levels may indicate fatty acid overload (e.g., from fasting, illness, or enzyme defects), while low levels could suggest carnitine deficiency or transport disorders. Always discuss results with your healthcare provider.
How long does it take to get results?
Results are typically available within 2–5 business days, depending on lab processing and follow-up needs. Your doctor will explain how to interpret them in the context of your health.
Can diet affect this test?
Yes, certain foods (e.g., high-fat meals) or fasting status may influence acylcarnitine levels. Follow your doctor’s specific instructions for diet or fasting before testing.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy