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COVID-19 Intubation Support Index (Serum/plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures levels of certain biomarkers in your blood that may help assess your risk of needing mechanical ventilation during COVID-19 infection.

Quick summary

["This test helps doctors evaluate your risk of needing a ventilator during illness."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
94813-3
Short code
Team COVID-19 Intub Conference
Synonyms
Team COVID-19 Intub Conference
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
team
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

The test evaluates a composite score derived from multiple biomarkers, including inflammatory markers and organ function indicators, which are analyzed together to predict the likelihood of requiring respiratory support. The exact combination of analytes may vary by lab protocol.

Why Might This Test Be Ordered?

Your healthcare provider may order this test if you are hospitalized with COVID-19 and are at high risk for severe illness, particularly if you have symptoms like difficulty breathing or low oxygen levels. It helps guide decisions about whether you need immediate respiratory support.

How Is the Sample Collected?

A blood sample is drawn from a vein, usually in your arm. The blood is processed to separate the serum or plasma for testing.

What Are the Possible Results?

Results are presented as a calculated score or ratio that reflects your risk profile. Higher scores may indicate a greater likelihood of needing mechanical ventilation.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: This test provides a snapshot of your body’s response to COVID-19, helping clinicians tailor treatment and support to prevent severe outcomes. While not a definitive predictor, it supports early intervention strategies to improve outcomes.

Short name

COVID-19 Intubation Support Marker

Frequently asked questions

Will I Need to Fast Before This Test?
No fasting is required for this test, as it involves a blood draw without dietary restrictions.
How Long Does It Take to Get Results?
Results are typically available within 24 to 48 hours, depending on lab processing times.
What If My Results Are Abnormal?
If your results suggest a higher risk of needing ventilation, your healthcare team will discuss next steps, which may include closer monitoring, adjustments to treatment, or additional interventions.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy