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Testosterone/Creatinine Ratio, Urine

Published: August 9, 2026Updated: August 16, 2026

Measures urine testosterone relative to urine creatinine, helping account for variations in urine concentration.

Quick summary

["This test helps assess testosterone excretion while adjusting for how concentrated the urine is."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
108528-1
Short code
Testost/Creat Msmt Ur
Synonyms
Testost/Creat Msmt Ur
Category
kidney
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

This urine test measures the amount of testosterone relative to the amount of creatinine in the same urine sample. Creatinine is used as a marker of urine concentration, so the ratio helps reduce the effect of variation in urine concentration.

Why might I need this test?

Your clinician may use this test to evaluate testosterone production, investigate symptoms of excess androgen activity, or monitor certain hormone treatments. It may be ordered for concerns such as unusual hair growth, acne, voice deepening, or menstrual changes.

How is the test performed?

You provide a urine sample according to the laboratory’s instructions. The laboratory measures testosterone and creatinine and calculates the testosterone-to-creatinine ratio. The type and collection period, such as a single sample or a timed collection, depend on the order.

How do I prepare for the test?

Follow the collection instructions provided by your clinician or laboratory. If a timed or 24-hour collection is ordered, collect all urine for the specified period and record the start and end times. Tell the healthcare team about medicines or supplements that may affect hormone results.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Urine testosterone/creatinine ratio

Frequently asked questions

Is this the same as a blood testosterone test?
No. This test measures testosterone in urine and compares it with urine creatinine. A blood testosterone test measures testosterone in the bloodstream and is used for different clinical purposes.
Why is creatinine included in the test?
Creatinine helps indicate how concentrated the urine is. Including it allows the laboratory to compare testosterone with creatinine rather than interpreting testosterone alone, which can be affected by variations in urine concentration.
Do I need to collect a 24-hour urine sample?
Not always. Some orders use a single urine sample, while others require a timed collection. Follow the specific collection instructions given by your healthcare provider or laboratory.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy