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Testosterone/Creatinine Ratio, Urine

Published: August 9, 2026Updated: August 16, 2026

A urine test that measures testosterone relative to creatinine, which helps account for urine concentration and can help assess testosterone production.

Quick summary

["This test helps evaluate testosterone production while reducing the effect of variations in urine concentration."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
13486-6
Short code
Testost/Creat Ur
Synonyms
Testost/Creat Ur
Category
kidney
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

The urine testosterone/creatinine ratio measures the amount of testosterone in urine compared with the amount of creatinine. Creatinine is used as a marker of urine concentration, so the ratio can provide a more stable estimate of testosterone excretion than a testosterone measurement alone.

Why might I need this test?

This test may be used to evaluate testosterone production or changes in testosterone levels. It can be especially useful when urine concentration varies or when monitoring treatment related to hormonal disorders.

How is the test performed?

A urine sample is collected and analyzed in a laboratory. The laboratory measures testosterone and creatinine and calculates their ratio. The type of urine collection, such as a single specimen or a timed collection, depends on the test ordered by your clinician.

How do I prepare for the test?

Follow the collection instructions provided by your clinician or laboratory. It may be necessary to collect the first urine of the morning or at a specific time. Tell the laboratory if you are pregnant, taking hormones or other medicines that affect testosterone, or if the test is being performed to monitor treatment.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

A low ratio may be associated with reduced testosterone production, while a high ratio may reflect increased testosterone production or the effects of testosterone therapy. Interpretation depends on the person’s age, sex, clinical situation, collection method, and medicines, so results should be reviewed by a healthcare professional.

Short name

Urine Testosterone/Creatinine Ratio

Frequently asked questions

Why is creatinine included in this urine test?
Creatinine helps show how concentrated the urine is. Dividing testosterone by creatinine reduces the influence of changes in urine concentration.
Does a low result always mean low testosterone?
No. A low ratio can reflect reduced testosterone production, but factors such as urine collection, kidney function, medicines, and the timing of the sample may also affect the result.
Can this test be used to monitor hormone treatment?
Yes, it may help monitor testosterone levels during treatment. Your clinician will interpret the result alongside the treatment being used and other relevant tests.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy