Skip to content

Testosterone and Creatinine Ratio, Urine

Published: August 9, 2026Updated: August 16, 2026

This urine test measures testosterone relative to creatinine, which helps account for differences in urine concentration.

Quick summary

["The ratio can help evaluate androgen excess when interpreted with symptoms, medical history, and other hormone tests."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
34380-6
Short code
Testost/Creat Ur-sRto
Synonyms
Testost/Creat Ur-sRto
Category
kidney
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

This test measures the amounts of testosterone and creatinine in urine and calculates their ratio. Creatinine is used as a reference because urine output and concentration can vary.

Why might I need this test?

A urine testosterone/creatinine ratio may be used to evaluate excess androgen activity or to help assess hormonal conditions. It may be considered along with symptoms such as irregular periods, acne, increased body hair, or voice deepening.

How is the test performed?

A urine sample is tested for testosterone and creatinine, and the laboratory calculates their ratio. Your care team will explain whether a single urine collection or a timed collection is required.

How do I prepare for the test?

Follow the collection instructions provided by your clinician or laboratory. If a timed collection is requested, record all urine collected during the specified period and store the container as directed.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

An elevated urine testosterone/creatinine ratio may suggest increased androgen production, such as with polycystic ovary syndrome, congenital adrenal hyperplasia, or an androgen-secreting tumor. A lower ratio may occur with reduced testosterone production or other hormonal disorders. Results should be interpreted using age, sex, symptoms, collection method, and other hormone tests.

Short name

Urine testosterone/creatinine ratio

Frequently asked questions

Is this the same as a blood testosterone test?
No. This test measures testosterone in urine and compares it with urine creatinine. A blood testosterone test is a separate test and may be used for additional evaluation.
Why is creatinine included in the test?
Urine can be more or less concentrated from one collection to another. Creatinine helps the laboratory account for that variation when calculating the testosterone ratio.
Do I need to fast for this test?
Fasting is generally not required, but follow your clinician's instructions. If timed urine collection is requested, careful adherence to the collection period is important.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy