Testosterone in Cerebrospinal Fluid (CSF)

Why Might This Test Be Ordered?

Your healthcare provider may recommend this test if you have symptoms or conditions linked to hormonal imbalances in the brain, such as unexplained headaches, neurological symptoms, or suspected pituitary disorders. It can also be part of a broader evaluation for conditions like precocious puberty, hormonal tumors, or metabolic disorders affecting the central nervous system.

What Does This Test Involve?

A small sample of your cerebrospinal fluid is collected through a procedure called a lumbar puncture (spinal tap). This involves inserting a needle into your lower back to draw fluid from your spinal canal. The sample is then sent to a lab for analysis.

What Are Common Uses of This Test?

CSF testosterone levels may be checked to diagnose or monitor conditions where hormonal imbalances in the brain play a role, such as evaluating for central precocious puberty, assessing for pituitary or hypothalamic tumors, or investigating symptoms related to hormonal deficiencies or excesses in the central nervous system.

What Should You Expect Before the Test?

Prepare by staying hydrated and avoiding heavy meals before the procedure. You may be asked to empty your bladder before the test. Inform your provider about any medications you’re taking, especially blood thinners, as they may affect the procedure.