Tetramethylbenzidine (TMB) substrate concentration in a qualitative immunoassay probe for detecting antibodies against tetanus toxoid
This test checks if your body has produced antibodies to protect against tetanus, a serious bacterial infection. Antibodies are proteins your immune system makes in response to exposure to tetanus toxin.
["This test helps determine if you’ve been adequately vaccinated or exposed to tetanus and may need booster protection."]
Key facts at a glance
- LOINC
- 105815-5
- Short code
- tetM Ct Bld Pos Qn NAA+probe
- Synonyms
- tetM Ct Bld Pos Qn NAA+probe
- Category
- chemistry
- Sample
- whole-blood
- Container
- Lavender-top (EDTA)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- probe-amp-tar
- Specimen volume
- 3 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
Why This Test Is Done
Your healthcare provider may recommend this test if you have a high-risk exposure to tetanus (e.g., deep wound, puncture), recent tetanus vaccination concerns, or if you’re planning a trip to areas with limited vaccination access. It’s also used in screening for patients with immunocompromising conditions.
How the Test Works
A small blood sample is taken to detect specific antibodies against tetanus toxoid. The test uses a qualitative immunoassay (often a rapid probe) that reacts with these antibodies if present, indicating immunity.
What to Expect Before the Test
No special preparation is needed. Wear comfortable clothing for easy access to your arm for the blood draw. Avoid eating or drinking for 1 hour before the test if instructed by your provider.
What to Expect During the Test
A healthcare professional will insert a small needle into your arm to draw blood. You may feel a slight pinch, but the process usually takes just a few minutes. The sample is then analyzed in a lab to check for antibody presence.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
A positive result means your body has produced antibodies against tetanus, suggesting immunity. A negative result indicates no detectable antibodies, which may mean you’re not protected and could require vaccination. This test is critical for high-risk patients, travelers, or those with weakened immune systems.
Short name
Tetanus Antibody Screening (Qualitative)
Frequently asked questions
What does a positive result mean?
Can I get tetanus even if my antibody test is positive?
How often should I get this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy