Genetic mutation analysis for TGN1 (TGF-β family member 1) via whole blood DNA
This test checks for specific genetic changes in the TGF-β1 gene, which may be linked to certain inherited conditions affecting how your body produces proteins involved in tissue growth and repair.
["This test helps identify possible genetic risks for rare disorders related to TGF-β1 function in blood samples."]
Key facts at a glance
- LOINC
- 48602-7
- Short code
- TGM1 gene Mut Anl Bld/T
- Synonyms
- TGM1 gene Mut Anl Bld/T
- Category
- chemistry
- Sample
- whole-blood
- Container
- Lavender-top (EDTA)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- molgen
- Specimen volume
- 3 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
Why This Test Might Be Ordered
Your healthcare provider may recommend this test if you have a family history of conditions like fibrodysplasia ossificans progressiva (FOP) or other connective tissue disorders, or if you’re at risk due to genetic screening for inherited mutations.
What to Expect Before the Test
No special preparation is needed. You’ll provide a small blood sample, similar to a routine blood draw. The sample is collected by a healthcare professional and sent to a lab for genetic analysis.
What the Results Mean
Results will indicate whether the tested genetic mutation is present. If found, it may confirm a genetic predisposition to certain conditions. Results are discussed with your doctor to guide further testing or management plans.
Common Conditions Linked to This Mutation
Mutations in the TGF-β1 gene are rarely associated with well-defined clinical syndromes. However, they may contribute to conditions affecting connective tissue or immune responses, though symptoms can vary widely.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical significance: This test is primarily used for genetic counseling and risk assessment in individuals with a family history of TGF-β-related disorders or those undergoing hereditary mutation screening. Results may influence future medical management or reproductive planning.
Short name
TGF-β1 Gene Mutation Test
Frequently asked questions
What does a positive result mean for my health?
How often should I get this test?
Can lifestyle changes affect this test result?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy