Protein Electrophoresis (Serum/Plasma) with Bromocresol Green (BCG) Dye Binding

What This Test Measures

The test uses a technique called electrophoresis to separate blood proteins into different fractions. A dye called bromocresol green binds to certain protein groups, allowing for precise measurement of their relative amounts. This helps identify shifts in protein levels that may indicate underlying health issues.

Why It’s Done

Doctors order this test to diagnose or monitor conditions affecting protein metabolism, such as liver disease (e.g., cirrhosis), kidney disease, or hereditary protein disorders. It may also be used to evaluate nutritional status or screen for conditions like multiple myeloma.

Sample Collection and Preparation

A blood sample is drawn from a vein, typically in your arm. The blood is then processed to separate serum or plasma, which is sent to the lab for testing. No special preparation is needed, but fasting may be advised depending on your doctor’s instructions.

Interpretation and Results

Results show the relative amounts of different protein fractions, often displayed as a graph or pattern. Abnormal patterns may indicate low or high levels of specific proteins, which can signal conditions like protein loss in urine (nephrotic syndrome), liver dysfunction, or immune system disorders.