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Prostate-Specific Antigen (PSA) Immunoassay (Quantitative)

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of prostate-specific antigen, a protein produced by the prostate gland, often checked to monitor prostate health or screen for prostate cancer.

Quick summary

["PSA levels help assess prostate health and guide decisions about further testing or treatment."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
87989-0
Short code
T gondii DNA Mar Ql NAA+probe
Synonyms
T gondii DNA Mar Ql NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Doctors may order a PSA test to: screen for early signs of prostate cancer, especially in men at higher risk; monitor progression of prostate cancer if already diagnosed; evaluate symptoms like urinary issues that might suggest prostate problems; or check for prostate inflammation or infection.

What to Expect Before the Test

No special preparation is needed, but you may be asked to avoid ejaculation for 2–4 days before testing to get a more accurate result. If you have recent prostate procedures, your doctor may advise waiting.

During the Test

A blood sample is drawn from a vein, usually in your arm. You may feel a brief pinch, but it’s quick and not painful. The sample is sent to a lab for analysis using an immunoassay method to detect PSA.

What the Results Mean

Results are not interpreted alone—they’re compared to your age, overall health, and symptoms. Higher-than-normal levels can signal prostate issues, but they don’t always mean cancer. Your doctor will discuss findings with you.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

PSA Level

Frequently asked questions

PSA levels can rise due to benign prostate conditions (like enlargement or inflammation), but they’re also a key indicator of prostate cancer. Regular monitoring helps detect changes early, improving treatment options.
What is a normal PSA level? PSA levels vary widely by age and health. Your doctor will use your specific results in context to guide next steps.
Can diet or medications affect PSA levels? Certain foods (like tomatoes or lycopene-rich foods) or medications (e.g., finasteride) may influence PSA. Always discuss your medications and diet with your doctor before testing.
How often should I get this test? Frequency depends on your risk factors, age, and health status. Your doctor will recommend a schedule based on your individual needs.
Is there any risk or discomfort with this test? The blood draw is minor and temporary discomfort is common. Rarely, there may be bruising or slight pain at the site.
What if my PSA level is elevated? If your PSA level is higher than expected, your doctor may recommend further tests (like a digital rectal exam or biopsy) to investigate the cause.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy