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D-dimer, quantitative (plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of D-dimer, a protein fragment produced when blood clots break down. It helps assess whether you’re at risk of blood clots or have a condition like deep vein thrombosis (DVT) or pulmonary embolism.

Quick summary

["D-dimer helps diagnose or rule out blood clots with a simple blood test."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
87984-1
Short code
T gondii DNA Tiss Ql NAA+probe
Synonyms
T gondii DNA Tiss Ql NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order a D-dimer test to check for signs of abnormal blood clotting. Common reasons include investigating symptoms like leg swelling, chest pain, or unexplained shortness of breath, which could signal conditions like DVT or pulmonary embolism. It may also be used in patients with known clotting disorders or those undergoing certain treatments that affect blood clotting.

How Is the Test Performed?

A small blood sample is drawn from a vein, usually in your arm. The blood is then processed to measure D-dimer levels. This test is typically done in a lab and may take a few hours to complete, depending on the lab’s workflow.

What Do My Results Mean?

High levels of D-dimer often suggest recent clot formation, which can indicate conditions like DVT or pulmonary embolism. Low or normal levels usually mean there is little to no active clotting happening. However, a negative test does not definitively rule out a clot in all cases, so your doctor may recommend additional testing if needed.

What Are the Possible Risks?

The most common risk of a blood draw is a slight bruising, swelling, or discomfort at the site where the needle was inserted. Rarely, there may be a small risk of infection or excessive bleeding, though these are uncommon with proper medical procedures.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: D-dimer plays a key role in diagnosing and managing blood clotting disorders. Elevated levels are strongly associated with active clot formation and can guide treatment decisions, such as anticoagulant therapy. However, it is not a standalone test for diagnosing clots—results should be interpreted alongside clinical findings and other tests.

Short name

D-dimer

Frequently asked questions

What does a high D-dimer level mean?
A high D-dimer level suggests there may be recent clot activity, which could indicate conditions like deep vein thrombosis (DVT) or pulmonary embolism. Your doctor will consider this result along with your symptoms and other tests to determine the next steps.
Can a low D-dimer level rule out blood clots completely?
A low or normal D-dimer level is unlikely to rule out blood clots entirely, as some people may have clots without elevated D-dimer levels. Your doctor may still recommend further testing, such as imaging studies, to investigate symptoms like swelling or chest pain.
How often should I get a D-dimer test?
The frequency of D-dimer testing depends on your medical condition, symptoms, and treatment plan. Your doctor will determine how often you need this test based on your individual needs, such as monitoring for clotting risks or evaluating treatment effectiveness.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy