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Prostate-Specific Antigen (PSA) in Serum by Immunoassay (with Probe)

Published: August 9, 2026Updated: August 16, 2026

This test measures levels of prostate-specific antigen (PSA), a protein produced mainly by the prostate gland. It helps assess prostate health, especially in men at risk for prostate cancer or other prostate-related conditions.

Quick summary

["PSA levels can guide discussions about prostate health and potential screening needs."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
108084-5
Short code
T gondii DNA Ur Ql NAA+probe
Synonyms
T gondii DNA Ur Ql NAA+probe
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order a PSA test to monitor prostate health, especially if you have symptoms like frequent urination, pain during urination, or an elevated risk due to age, family history, or other factors. It can also be used to screen for prostate cancer or evaluate treatment progress.

What Does a High PSA Level Mean?

Elevated PSA levels can indicate conditions such as benign prostatic hyperplasia (enlarged prostate), prostate inflammation, or prostate cancer. However, other factors, like age, race, or recent ejaculation, can also influence PSA levels. Results should always be interpreted by your healthcare provider in the context of your overall health.

What Does a Low PSA Level Mean?

Low PSA levels are less commonly associated with prostate issues but may occur in younger men or those with certain medical conditions. They can also be influenced by factors like low testosterone or certain medications. Your doctor will consider the full clinical picture.

How Is This Test Performed?

A blood sample is drawn from a vein, usually in your arm. The sample is sent to a lab where it is analyzed using an immunoassay method to detect PSA protein levels. This test does not require fasting or special preparation beyond standard blood draw procedures.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: PSA Testing Plays a Key Role in Prostate Health Monitoring

Short name

PSA Test

Frequently asked questions

How often will I need this test?
The frequency depends on your age, medical history, and symptoms. Men under 55 typically do not routinely get PSA tests unless recommended by a doctor. Men aged 55 and older may discuss screening with their healthcare provider, often every 1–2 years. Regular monitoring may be recommended for those with a family history of prostate cancer or other risk factors.
What are the possible side effects of this test?
Most people experience only mild discomfort or bruising at the needle insertion site. Rarely, there may be slight swelling or pain, but these symptoms usually resolve quickly. If you experience excessive bleeding, severe pain, or signs of infection, contact your healthcare provider.
Can lifestyle changes affect PSA levels?
Yes, certain lifestyle factors may influence PSA levels. Recent ejaculation can temporarily raise PSA levels, so some tests may be scheduled before sexual activity. Dietary changes, exercise, or certain medications (like finasteride) can also have minor effects, but they are not the primary focus of PSA testing.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy