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Toxoplasma gondii IgG Antibody (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures the presence of antibodies in your blood that your immune system produces in response to the parasite Toxoplasma gondii, which can cause infections like toxoplasmosis.

Quick summary

["It helps determine if you’ve been exposed to the parasite and whether your body has built immunity."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
13286-0
Short code
T gondii IgG sp2 Ser-aCnc
Synonyms
T gondii IgG sp2 Ser-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Doctors may order this test if you have symptoms of toxoplasmosis, such as fever, muscle aches, or swollen lymph nodes, especially after exposure to undercooked meat, soil, or contaminated water. It’s also used in pregnant women to check for infection, as toxoplasmosis can pose risks to a developing fetus. Additionally, it may be part of routine screening for immunocompromised individuals (e.g., those with HIV/AIDS, cancer, or undergoing organ transplants).

What to Expect Before the Test

No special preparation is needed for this blood test. You may have a small needle inserted into your arm to draw blood, which usually takes a few minutes. If you’re pregnant or immunocompromised, let your healthcare provider know before the test.

What the Test Results Mean

A positive result means your body has produced antibodies against Toxoplasma gondii, indicating past exposure. A negative result suggests you likely haven’t been exposed recently. However, results can vary based on your immune status and timing of exposure. Your doctor will interpret results in the context of your symptoms and medical history.

Possible Side Effects

Most people experience mild side effects from blood drawing, such as a slight bruise, soreness, or swelling at the injection site. Rarely, you might feel lightheaded or dizzy, especially if you stand up too quickly. If you experience severe pain, excessive bleeding, or signs of infection (e.g., redness, warmth, or pus), contact your healthcare provider.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

IgG Antibody to Toxoplasma

Frequently asked questions

IgG antibodies to Toxoplasma gondii are typically detected months to years after initial infection. While they indicate past exposure, they don’t always confirm active infection. For active toxoplasmosis, doctors may also check for IgM antibodies or other markers. This test is critical for monitoring pregnant women, immunocompromised patients, and those with symptoms suggestive of infection, as prompt treatment can prevent complications.
Why might my doctor ask for this test if I’ve already had a positive result before?
Your doctor may repeat the test to confirm immunity, especially if you’re pregnant, immunocompromised, or have been recently exposed to risk factors (e.g., eating raw meat, gardening). It helps ensure your body remains protected against potential reinfection or complications.
No, this test requires a blood sample drawn in a clinical setting. While some antibody tests are available at home, IgG testing typically requires lab confirmation for accuracy, especially in high-risk groups.
What if my test results are inconclusive?
If your results are unclear, your doctor may order additional tests, such as IgM antibody testing (for recent infection) or other diagnostic tools. They’ll work with you to determine the best next steps based on your symptoms and medical history.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy