Total Bilirubin (Serum)
This test measures the total amount of bilirubin in your blood, a yellow pigment produced when red blood cells break down. Bilirubin is normally processed by the liver and excreted in bile.
["Bilirubin helps diagnose liver and bile duct issues, including jaundice."]
Key facts at a glance
- LOINC
- 42343-4
- Short code
- T gondii Spec Other Stn
- Synonyms
- T gondii Spec Other Stn
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- xxx-stain
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
This test gives your healthcare provider important information about how your body is working. Finding problems early can help you and your care team make timely decisions about treatment, lifestyle changes, or additional testing that may protect your long-term health.
Bilirubin is a byproduct of hemoglobin breakdown. High levels can indicate problems like liver disease, gallbladder issues, or hemolysis (red blood cell destruction). Low levels may suggest liver dysfunction or other conditions affecting bilirubin metabolism.
Before the test, your provider will give you specific instructions, which may include fasting for a certain number of hours, avoiding certain foods or drinks, or temporarily pausing some medications. Tell your care team about all medicines, supplements, and allergies you have, and ask questions if anything is unclear.
No special preparation is needed. You may eat and drink normally before your blood draw. Tell your provider about any medications or supplements you take, as they could affect results.
During the test, a trained member of your care team will carry out the procedure in a comfortable setting. The exact steps depend on the type of test, but most take only a short time. You may be asked to sit or lie still, and the team will explain each step as it happens so you know what to expect.
A healthcare provider will collect a blood sample from a vein in your arm using a needle. You may feel slight discomfort, but it usually lasts only a few seconds. The blood is then sent to a lab for analysis.
Your results may fall within a normal range or show values that need a closer look. Normal results usually mean no signs of concern at this time, while abnormal results do not always indicate a serious problem. Your provider will review the results with you, explain what they mean, and discuss any follow-up steps if needed.
Results are typically reported in milligrams per deciliter (mg/dL). Higher than normal levels may signal jaundice, liver disease, or blockages in the bile ducts. Lower levels may indicate liver problems or other metabolic issues.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
Total Bilirubin
Frequently asked questions
What does an abnormal bilirubin level mean?
Can I eat or drink anything before this test?
What if I have a reaction to the needle?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy