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Total Bilirubin (Serum)

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of bilirubin in your blood, a yellow pigment produced when red blood cells break down. Bilirubin is normally processed by the liver and excreted in bile.

Quick summary

["Bilirubin helps diagnose liver and bile duct issues, including jaundice."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
42343-4
Short code
T gondii Spec Other Stn
Synonyms
T gondii Spec Other Stn
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
xxx-stain
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

This test gives your healthcare provider important information about how your body is working. Finding problems early can help you and your care team make timely decisions about treatment, lifestyle changes, or additional testing that may protect your long-term health.

Bilirubin is a byproduct of hemoglobin breakdown. High levels can indicate problems like liver disease, gallbladder issues, or hemolysis (red blood cell destruction). Low levels may suggest liver dysfunction or other conditions affecting bilirubin metabolism.

Before the test, your provider will give you specific instructions, which may include fasting for a certain number of hours, avoiding certain foods or drinks, or temporarily pausing some medications. Tell your care team about all medicines, supplements, and allergies you have, and ask questions if anything is unclear.

No special preparation is needed. You may eat and drink normally before your blood draw. Tell your provider about any medications or supplements you take, as they could affect results.

During the test, a trained member of your care team will carry out the procedure in a comfortable setting. The exact steps depend on the type of test, but most take only a short time. You may be asked to sit or lie still, and the team will explain each step as it happens so you know what to expect.

A healthcare provider will collect a blood sample from a vein in your arm using a needle. You may feel slight discomfort, but it usually lasts only a few seconds. The blood is then sent to a lab for analysis.

Your results may fall within a normal range or show values that need a closer look. Normal results usually mean no signs of concern at this time, while abnormal results do not always indicate a serious problem. Your provider will review the results with you, explain what they mean, and discuss any follow-up steps if needed.

Results are typically reported in milligrams per deciliter (mg/dL). Higher than normal levels may signal jaundice, liver disease, or blockages in the bile ducts. Lower levels may indicate liver problems or other metabolic issues.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Total Bilirubin

Frequently asked questions

What does an abnormal bilirubin level mean?
How often you should get this test depends on your age, overall health, risk factors, and the reason it was ordered. Your healthcare provider will recommend a schedule that is right for you, so it is best to follow their guidance and ask at each visit whether testing is due.
Can I eat or drink anything before this test?
Most people find this test causes little or no pain. You may feel brief discomfort, pressure, or a quick pinch at certain moments, but these sensations are usually mild and go away soon. If you are worried, tell your care team beforehand so they can help you stay as comfortable as possible.
What if I have a reaction to the needle?
If you experience dizziness, nausea, or a severe reaction, inform the healthcare provider immediately. They may slow your heart rate or use a different vein to minimize discomfort.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy