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Aldosterone and Creatinine, Urine

Published: August 9, 2026Updated: August 16, 2026

Measures aldosterone and creatinine in urine. Creatinine may be used to account for urine concentration, and the results may be reported as an aldosterone-to-creatinine ratio.

Quick summary

["This test helps evaluate aldosterone excretion while adjusting for differences in urine concentration."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
30515-1
Short code
THaldost/Creat Ur
Synonyms
THaldost/Creat Ur
Category
kidney
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

This test measures aldosterone, a hormone that helps regulate blood pressure and fluid balance, along with creatinine, a waste product used to assess how concentrated the urine is.

Why might I need this test?

It may be ordered when high blood pressure, low potassium, or other findings raise concern for excess aldosterone. The results can help evaluate the adrenal glands and the renin-aldosterone system.

How is the test performed?

A urine sample is collected and analyzed in the laboratory. Your clinician will provide instructions about the collection amount and whether a timed or 24-hour collection is required.

How do I prepare for the test?

Follow the collection instructions provided by the laboratory or clinician. Tell the healthcare team about medicines, supplements, and recent changes in salt intake, because they can affect aldosterone results.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

An elevated urine aldosterone level or aldosterone-to-creatinine ratio may occur with primary aldosteronism, a cause of high blood pressure and sometimes low potassium. Other conditions and certain medicines can also alter the result, so abnormal findings require clinical interpretation and often confirmatory testing.

Short name

Urine aldosterone and creatinine

Frequently asked questions

Why is creatinine included with urine aldosterone?
Creatinine helps show how concentrated the urine is. Including it allows aldosterone to be compared with creatinine, which can reduce the effect of variations in urine concentration.
Do I need to collect all of my urine for 24 hours?
That depends on the test ordered. Some urine aldosterone tests use a single sample, while others require a complete 24-hour collection, so follow the specific instructions you receive.
Can medicines affect the results?
Yes. Several blood pressure medicines, diuretics, corticosteroids, and other drugs may affect aldosterone levels. Do not stop prescribed medicines without discussing them with your clinician.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy