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Thallium and Creatinine, 24-Hour Urine

Published: August 9, 2026Updated: August 16, 2026

Measures thallium, a toxic heavy metal, and creatinine in urine collected over 24 hours. Creatinine helps assess whether the collection is complete.

Quick summary

["This test can identify recent thallium exposure and help determine how much thallium the body is eliminating."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
29938-8
Short code
Thallium/Creat 24h Ur
Synonyms
Thallium/Creat 24h Ur
Category
kidney
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

This test measures the amount of thallium in all urine collected over 24 hours. It also measures urine creatinine, which is used to help evaluate the completeness of the collection and the adequacy of the sample.

Why might I need this test?

The test may be ordered if a person has symptoms of heavy-metal poisoning, a known or suspected exposure to thallium, or occupational contact with substances containing thallium. It can also be used to follow thallium levels during evaluation or recovery.

How is the test performed?

You empty your bladder at the start of the collection period and then collect all urine for the next 24 hours, including the final collection. The urine is brought to the laboratory for measurement of thallium and creatinine.

How do I prepare for the test?

Use the container supplied by the laboratory and follow its collection instructions exactly. Tell the clinician about possible occupational, environmental, medication, or supplement exposure, and do not stop medicines or make major diet changes unless instructed.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

An elevated urine thallium level may indicate recent exposure to thallium and can be associated with toxicity. The meaning of the result depends on the amount exposed, timing of collection, symptoms, and other clinical findings. Urine creatinine is used to help assess collection adequacy; an unusually low result may suggest an incomplete collection or very dilute urine.

Short name

24-Hour Urine Thallium and Creatinine

Frequently asked questions

What does thallium exposure mean?
Thallium is a heavy metal that can be harmful to the nervous system, gastrointestinal tract, and other organs. Exposure can occur in some workplaces or through contaminated substances.
Why is urine collected for 24 hours?
A 24-hour collection captures thallium released by the body over a full day. This can provide a more representative picture than a single urine sample.
Why is creatinine measured with thallium?
Creatinine helps determine whether all urine was collected and whether the sample is adequately concentrated. It is used to support, rather than replace, clinical interpretation.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy