Tetrahydrodeoxycorticosterone/Creatinine, 24-Hour Urine — Mass Ratio
A 24-hour urine test that measures tetrahydrodeoxycorticosterone relative to creatinine to help assess adrenal steroid production.
["This test can help identify certain disorders that cause excess adrenal steroid production."]
Key facts at a glance
- LOINC
- 81793-2
- Short code
- TH-DC/Creat 24h Ur-sRto
- Synonyms
- TH-DC/Creat 24h Ur-sRto
- Category
- kidney
- Sample
- urine
- Container
- Sterile urine container
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 10 mL
- Stability
- Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
What is this test?
This test measures tetrahydrodeoxycorticosterone, an adrenal steroid, in urine collected for 24 hours. The result is compared with the amount of creatinine in the same collection, which helps account for differences in urine concentration.
Why might I need this test?
This test may be used when a clinician is evaluating unusual adrenal hormone levels or suspected congenital adrenal hyperplasia. It is most often considered when symptoms suggest an imbalance in adrenal steroid production.
How is the test performed?
You collect all urine produced during a 24-hour period using the container and instructions provided by the laboratory. The laboratory then measures tetrahydrodeoxycorticosterone and creatinine and calculates their ratio.
How do I prepare for the test?
Follow the laboratory's collection instructions exactly, including when to start and stop the collection. Keep and submit the entire collection as directed, note the collection times, and do not stop prescribed medicines without discussing them with your clinician.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
An elevated tetrahydrodeoxycorticosterone-to-creatinine ratio may indicate increased production of certain adrenal steroids. This can occur in disorders affecting adrenal hormone production, including some forms of congenital adrenal hyperplasia. The result must be interpreted with symptoms, other hormone tests, and the clinician's assessment.
Short name
24-Hour Urine THDOC/Creatinine
Frequently asked questions
Why is the result divided by creatinine?
How is a 24-hour urine collection done?
Does one abnormal result confirm a diagnosis?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy