Theophylline Level (Mass Concentration)
This test measures the amount of theophylline, a medication derived from tea leaves, in your blood. It helps monitor your levels to ensure they stay within safe therapeutic ranges.
["This test checks if your theophylline medication is working properly and at safe levels."]
Key facts at a glance
- LOINC
- 4048-5
- Short code
- Theophylline Sal-mCnc
- Synonyms
- Theophylline Sal-mCnc
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 10
- Ref high
- 20
- Critical range
- — – 20 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Is Done
Doctors may order a theophylline test if you’re taking medications containing theophylline (such as aminophylline or theophylline itself) to manage conditions like asthma, chronic obstructive pulmonary disease (COPD), or other breathing-related issues. It helps prevent dangerous levels of the medication that could cause side effects or health risks.
What to Expect Before the Test
No special preparation is needed for this test. You may have a small needle inserted into a vein in your arm, or a blood sample may be collected from a finger prick. If you’re on a regular medication schedule, let your healthcare provider know to ensure timing aligns with your usual dose.
What the Test Results Mean
Theophylline levels are measured in micrograms per milliliter (mcg/mL). Results help determine if your dose is too high or too low. High levels may cause nausea, rapid heart rate, or other symptoms, while low levels might mean your medication isn’t working effectively.
Possible Side Effects or Risks
While rare, very high theophylline levels can lead to serious side effects like seizures, irregular heartbeat, or even heart failure. Your doctor will adjust your medication based on these results to keep you safe.
Reference range
Therapeutic: 10-20 mcg/mLN/A
No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
Theophylline
Frequently asked questions
What causes theophylline levels to be checked?
What happens if my theophylline levels are too high?
Can I eat or drink before this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy