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Theophylline Concentration (Serum or Plasma)

Published: August 9, 2026Updated: August 17, 2026

This test measures the amount of theophylline, a medication derived from tea leaves, in your blood. Theophylline is used to treat breathing problems like asthma or chronic obstructive pulmonary disease (COPD).

Quick summary

["Your doctor may order this test to check if your theophylline levels are within the safe range for your treatment."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
46081-6
Short code
Theophylline Ur-sCnc
Synonyms
Theophylline Ur-sCnc
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Ref low
10
Ref high
20
Critical range
— – 20 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may recommend this test if you’re taking theophylline to manage breathing issues. They might also order it to monitor your response to the medication, check for side effects, or adjust your dose. This helps ensure the medication is effective and safe for you.

What to Expect Before the Test

No special preparation is needed for this test. You may have a small needle inserted into your arm or a blood sample drawn from a vein. If you’re taking theophylline, your provider may ask you to stop it temporarily before the test, depending on your situation.

What Happens During the Test?

A healthcare professional will collect a blood sample from a vein in your arm. The sample is then sent to a lab for analysis. The test measures the amount of theophylline in your blood, usually reported in micrograms per milliliter (mcg/mL).

What the Results Mean

Results will show your current theophylline level. High levels can cause side effects like nausea, rapid heartbeat, or trouble sleeping, while low levels may mean the medication isn’t working as intended. Your doctor will interpret the results in the context of your symptoms and treatment plan.

Reference range

Therapeutic: 10-20 mcg/mLN/A

Specimen: urine

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Theophylline is a bronchodilator used to relieve symptoms of asthma and COPD. Monitoring levels helps prevent toxicity (too much) or insufficient effectiveness (too little). Abnormal results may prompt dose adjustments, medication changes, or further evaluation of your breathing condition.

Short name

Theophylline Level

Frequently asked questions

What causes theophylline levels to be checked?
Your doctor may check your theophylline levels if you’re taking this medication to manage breathing issues, if you experience side effects like rapid heartbeat or nausea, or if your symptoms don’t improve as expected.
How long does it take to get the results?
Results are typically available within 1 to 2 business days, depending on your lab’s processing time. Your healthcare provider will contact you once they have the results.
Can I eat or drink before this test?
You can eat and drink normally before this test unless your doctor instructs otherwise. No special fasting is required.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy