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Thiopental concentration in serum/plasma (24-hour profile)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of the anesthetic drug thiopental in your blood over a 24-hour period. It helps doctors monitor how your body processes and eliminates this medication, especially after surgery or anesthesia.

Quick summary

["This test helps ensure safe drug levels during recovery from anesthesia."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
56697-6
Short code
Thiopental IgE Qn
Synonyms
Thiopental IgE Qn
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test if you’ve recently received thiopental, a fast-acting anesthetic, during surgery or medical procedures. It helps track how your body breaks down and removes the drug to prevent side effects like dizziness, confusion, or low blood pressure.

What to Expect Before the Test

No special preparation is needed. Blood is drawn from a vein in your arm, similar to other blood tests. You may feel a small pinch, but it usually doesn’t cause discomfort. If you’re on blood thinners, let your doctor know before the test.

What the Results Mean

Results show the concentration of thiopental in your blood at different times over 24 hours. While exact reference ranges vary by lab, your doctor will interpret these results in relation to your medical condition and treatment plan. Abnormally high or low levels may indicate how well your body is processing the drug.

Possible Side Effects or Considerations

Thiopental is generally safe when used as directed, but prolonged exposure or incorrect dosing can lead to side effects like low blood pressure, confusion, or respiratory issues. If you experience unusual dizziness, nausea, or irregular heartbeat after the test, contact your doctor immediately.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Monitoring Drug Metabolism and Safety

Short name

Thiopental Level (24h)

Frequently asked questions

What does a thiopental 24-hour profile help doctors assess?
This profile helps assess how quickly your body metabolizes thiopental, ensuring safe levels during recovery. It also helps prevent complications like drug accumulation (if metabolized too slowly) or premature elimination (if metabolized too quickly), which could affect anesthesia outcomes or recovery.
Can this test detect thiopental in other body fluids besides blood?
No, this test specifically measures thiopental in serum or plasma. While thiopental can appear in urine or other fluids, a 24-hour urine test would be needed for those measurements.
Why might my doctor request this test instead of a single blood draw?
A single blood draw only captures a snapshot of thiopental levels at one time. A 24-hour profile provides a full picture of how your body processes the drug over time, helping doctors tailor anesthesia plans more precisely and reduce risks of side effects.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy