Skip to content

Threonine concentration (serum/plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of threonine, an essential amino acid, in your blood. Threonine plays a role in metabolism, protein synthesis, and other bodily functions.

Quick summary

["Threonine levels can help assess amino acid balance and metabolic health."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
27179-1
Short code
Threonine Amn-sCnc
Synonyms
Threonine Amn-sCnc
Category
chemistry
Sample
fluid
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
2-5 mL
Stability
Room temperature: 2h, Refrigerated: 24h
Hemolysis max
300
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Doctors may order this test if you have symptoms like muscle weakness, fatigue, or unexplained weight changes that could suggest an amino acid disorder. It may also be part of broader metabolic screening, especially in cases of malnutrition, kidney disease, or genetic conditions affecting amino acid metabolism.

What Does the Test Involve?

A blood sample is drawn from a vein, usually in your arm. The blood is then sent to a lab for analysis. The test measures threonine concentration using a specialized biochemical method.

What Do Results Mean?

Results are typically reported as a mass concentration (e.g., in micromoles per liter). While reference ranges vary by lab, abnormal levels may indicate conditions like primary aminoaciduria, certain metabolic disorders, or other systemic health issues.

Common Causes of Abnormal Results

Low threonine levels may result from malabsorption, liver disease, or certain genetic disorders. High levels could be linked to overproduction, kidney issues, or specific metabolic syndromes.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Threonine Level

Frequently asked questions

Why might my doctor ask for this test?
Your doctor may recommend it if you have symptoms like unexplained fatigue, muscle weakness, or signs of malnutrition. It could also be part of a broader metabolic workup, especially if you have a family history of amino acid disorders or conditions affecting protein metabolism.
What are the typical reference ranges for this test?
Reference ranges vary by lab and method, so your results will be compared to the specific standards used at your facility. Abnormal values may prompt further testing or evaluation of diet, kidney function, or genetic factors.
Is this test painful?
The blood draw itself may cause mild discomfort, but most people tolerate it well. You can ask your healthcare provider about ways to minimize discomfort, such as choosing a less sensitive vein or using a tourniquet properly.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy