Threonine, Cerebrospinal Fluid, Mass Concentration
This test measures the amount of threonine, an amino acid, in cerebrospinal fluid (the fluid surrounding the brain and spinal cord).
["Threonine measurement in CSF can help evaluate certain metabolic or nutritional conditions affecting the central nervous system."]
Key facts at a glance
- LOINC
- 3006-4
- Short code
- Threonine CSF-mCnc
- Synonyms
- Threonine CSF-mCnc
- Category
- chemistry
- Sample
- csf
- Container
- Sterile tube
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 1-2 mL
- Stability
- Immediate analysis required, Refrigerated: 1h
- Hemolysis max
- 200
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
Threonine is one of the building blocks of protein (an amino acid) that the body uses to make proteins and other important molecules. This test determines how much threonine is present in a sample of cerebrospinal fluid, which is collected through a procedure called a lumbar puncture (spinal tap).
Why Doctors Order It
Your healthcare provider may order this test when evaluating suspected amino acid metabolism disorders, unusual neurological symptoms, or nutritional concerns. It is often part of a broader panel of amino acid testing rather than a stand-alone test, and results are interpreted alongside other findings.
How the Sample Is Collected
Cerebrospinal fluid is collected by a clinician during a lumbar puncture, where a thin needle is placed in the lower back to draw a small sample of fluid. The sample is then sent to a laboratory for analysis. Your care team will explain any preparation steps beforehand.
What Results Mean
Results are reported as a mass concentration of threonine in the fluid. Whether a value is considered normal depends on the laboratory's own reference range and on the individual's age and clinical context. Your provider will interpret the result in light of your symptoms and other test results, so discuss any questions directly with them.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Threonine levels in cerebrospinal fluid can be relevant in the workup of inherited amino acid metabolism disorders and some neurological or nutritional conditions. Because cerebrospinal fluid testing is specialized and reference ranges vary by laboratory, results should always be interpreted by a qualified clinician in the context of the full clinical picture.
Short name
CSF Threonine
Frequently asked questions
Is this test the same as a blood amino acid test?
Does an abnormal result mean I have a disease?
Is a lumbar puncture painful?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy