Threonine in Cerebrospinal Fluid (CSF)
This test measures the amount of threonine, an amino acid, found in your cerebrospinal fluid (the fluid surrounding your brain and spinal cord). It may be used to assess metabolic or neurological conditions.
["Threonine levels in CSF can help diagnose or monitor certain health issues."]
Key facts at a glance
- LOINC
- 22643-1
- Short code
- Threonine CSF-sCnc
- Synonyms
- Threonine CSF-sCnc
- Category
- chemistry
- Sample
- csf
- Container
- Sterile tube
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 1-2 mL
- Stability
- Immediate analysis required, Refrigerated: 1h
- Hemolysis max
- 200
- TAT
- 4–24 hours
- Order
- routine
Why This Test Might Be Ordered
Your healthcare provider may recommend this test if you have symptoms like headaches, seizures, or neurological problems that could be linked to metabolic disorders, genetic conditions, or other neurological issues. It might also be part of a broader evaluation for conditions affecting brain chemistry or fluid balance.
What to Expect Before the Test
No special preparation is typically needed. You may be asked to fast for a short period, depending on the clinic’s protocol. Your provider will explain any restrictions. Bring any medications you’re currently taking to your appointment.
What Happens During the Test
A healthcare professional will perform a lumbar puncture (spinal tap) to collect a small sample of CSF. This involves inserting a needle into your lower back and drawing fluid into a sterile container. You may feel pressure or mild discomfort, but it usually doesn’t last long.
What the Results Mean
Your results will be compared to standard reference ranges for threonine in CSF. Abnormal levels may suggest metabolic disorders, genetic conditions, or other neurological issues that require further evaluation by your healthcare team.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Elevated or decreased threonine levels in CSF can indicate underlying metabolic disorders, such as certain amino acidopathies, or conditions affecting the central nervous system. For example, high levels might be associated with disorders like homocystinuria or other inborn errors of metabolism. Low levels could be part of broader neurological assessments, though interpretation depends on clinical context and other test results.
Short name
CSF Threonine
Frequently asked questions
What causes abnormal threonine levels in CSF?
Will I need to take any special steps after the test?
Is this test painful?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy