Skip to content

: Thrombin Injection for Pseudoaneurysm (Procedure)

Published: August 9, 2026Updated: August 16, 2026

: This is a minimally invasive procedure in which a doctor injects a clotting agent called thrombin directly into a pseudoaneurysm to make the blood inside it clot and seal off the abnormal pouch.

Quick summary

[": Thrombin injection is a nonsurgical way to close a pseudoaneurysm by causing the pooled blood within it to clot."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
87148-3
Short code
Thromb inj for pseudoaneurysm
Synonyms
Thromb inj for pseudoaneurysm
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
imaging-modality
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

: What Is a Pseudoaneurysm?

: A pseudoaneurysm is a collection of blood that forms outside the wall of an artery but stays connected to it through a small opening. It is sometimes called a false aneurysm because it is not a true ballooning of the vessel wall; instead, it is contained by surrounding tissue. These often occur after a puncture to an artery, such as during a catheter procedure.

: What the Procedure Involves

: Using ultrasound guidance, the doctor locates the pseudoaneurysm and guides a thin needle through the skin into the blood-filled sac. A small amount of thrombin, a protein that promotes clotting, is injected. The thrombin causes the blood inside the sac to clot, and the clot blocks the connection to the artery. Ultrasound is used throughout to confirm the sac has been sealed.

: Why It Is Done

: Thrombin injection is typically offered when a pseudoaneurysm does not close on its own and is at risk of enlarging, rupturing, or causing symptoms such as pain or pressure on nearby structures. It is generally preferred over surgery because it is less invasive and can often be done without general anesthesia.

: What to Expect

: The procedure is usually quick and performed in an imaging or procedure room rather than an operating room. Local numbing medicine is used at the injection site. Many patients can go home the same day, though your care team will give specific instructions. Follow-up ultrasound is commonly scheduled to confirm the pseudoaneurysm has stayed closed.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

: NONE

Frequently asked questions

: Is thrombin injection painful?
: Most people feel only the sting of the numbing medicine at the skin. The injection itself is usually not painful, and the procedure is generally well tolerated.
: How soon does the pseudoaneurysm close after thrombin injection?
: The clotting usually happens within seconds to minutes during the procedure, and ultrasound is used right away to confirm the sac has sealed. Occasionally a repeat injection or additional treatment is needed.
: Can I go home the same day?
: Many patients can go home the same day, but this depends on your overall health and your care team's instructions. Follow-up imaging is typically arranged to confirm the result.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy