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Serum or plasma concentration of total bilirubin

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of bilirubin in your blood. Bilirubin is a yellow pigment produced when red blood cells break down, and it helps the liver process waste products.

Quick summary

["Bilirubin helps identify liver function and bile flow issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
93339-0
Short code
THSD7A IgG SerPl Ql IF
Synonyms
THSD7A IgG SerPl Ql IF
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
if
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why is this test done?

Your doctor may order this test to check for liver disease, bile duct blockages, or other conditions affecting how your body processes bilirubin. It can also help diagnose jaundice (yellowing of the skin and eyes) or monitor conditions like hemolytic anemia or Gilbert’s syndrome.

What does a result mean?

Higher than normal levels may suggest liver problems, bile duct issues, or red blood cell breakdown. Lower levels might indicate liver disease or certain genetic conditions. Your doctor will interpret results in the context of your overall health.

How is the test performed?

A blood sample is taken from a vein, usually in your arm. The sample is sent to a lab where bilirubin levels are measured using a specialized test that detects its presence in the serum or plasma.

What should I expect before the test?

No special preparation is needed, but avoid alcohol or certain medications that may affect liver function for a few days before testing. Tell your doctor about any medications you’re taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical significance: Elevated bilirubin often signals conditions like hepatitis, cirrhosis, gallstones, or hemolysis. Low levels may indicate liver disease or metabolic disorders. Early detection helps manage conditions like jaundice or bile duct obstructions.

Short name

Total bilirubin

Frequently asked questions

How long does it take to get results?
Results are typically available within 1–3 business days, depending on your lab’s processing time.
Can I eat or drink before this test?
You can eat and drink normally unless instructed otherwise by your doctor.
Does this test require fasting?
No fasting is required for this test.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy