Thyroglobulin Antibody Screening (Serum)
This test checks for antibodies against thyroglobulin, a protein produced by the thyroid gland. It helps identify autoimmune thyroid conditions, such as Hashimoto’s thyroiditis.
["Assessing potential autoimmune thyroid issues with antibody detection."]
Key facts at a glance
- LOINC
- 17705-5
- Short code
- Thyroglob IgM Ser-aCnc
- Synonyms
- Thyroglob IgM Ser-aCnc
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 82784
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Matters
Thyroglobulin antibodies can indicate an immune system attacking the thyroid, which may lead to thyroid dysfunction. This screening helps doctors monitor or diagnose conditions like Hashimoto’s thyroiditis or other autoimmune disorders affecting the thyroid.
How the Test Works
A small blood sample is drawn to detect thyroglobulin antibodies using an immunoassay method. This test measures the presence of these antibodies in your serum, helping to evaluate thyroid health and autoimmune activity.
What to Expect Before the Test
No special preparation is needed for this test. You may have fasting instructions depending on your doctor’s protocol, but generally, you can eat and drink normally before coming in. Wear comfortable clothing for easy access to your arm.
What to Expect After the Test
After the blood draw, you may feel slight discomfort or bruising at the site, but this usually fades quickly. You can resume normal activities immediately. Follow-up with your healthcare provider if you have any concerns or questions about your results.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Elevated levels of thyroglobulin antibodies may suggest an autoimmune response targeting the thyroid. This can be particularly important in patients with a history of thyroid cancer or those undergoing thyroid monitoring. Doctors use these results to guide treatment plans, such as managing symptoms or adjusting medication.
Short name
Thyroglobulin Antibodies (Screen)
Frequently asked questions
What does a positive result mean?
Will I need additional tests if my result is positive?
Can lifestyle changes affect this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy