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Thyroid Stimulating Hormone (TSH) with Serum Concentration Measurement

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of thyroid-stimulating hormone in your blood, which helps your thyroid gland produce hormones needed for metabolism and energy levels.

Quick summary

["Your doctor may order this test to check for thyroid problems, including underactive (hypothyroidism) or overactive (hyperthyroidism) thyroid function."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
96460-1
Short code
Thyrogl p thyrogl Ab neut SerPl IA-mCnc
Synonyms
Thyrogl p thyrogl Ab neut SerPl IA-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0.8
Ref high
1.2
Critical range
— – 5 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia
CPT
85610
SNOMED
396252006
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Doctors often use TSH testing as a first step to diagnose thyroid disorders. It’s especially useful when symptoms like fatigue, weight changes, or mood swings are present. TSH levels can also help monitor thyroid treatment progress or detect thyroid issues in people with no obvious symptoms.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for 8–12 hours before the test if your blood is drawn early in the morning. Avoid smoking or taking certain medications (like thyroid hormone) for 24 hours before testing, as they can affect results.

What the Results Mean

TSH results are interpreted based on your overall health, symptoms, and other lab tests. High TSH levels often indicate an underactive thyroid, while low levels may suggest an overactive thyroid. Your doctor will discuss these findings with you.

Common Causes of Abnormal Results

TSH levels can be affected by thyroid diseases (e.g., Hashimoto’s thyroiditis, Graves’ disease), pituitary disorders, pregnancy, or certain medications. Illness, stress, or thyroid surgery can also influence results.

Reference range

INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A

Specimen: serum

Inform your healthcare provider if you are taking blood thinners. No special preparation required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

TSH (Serum)

Frequently asked questions

What might cause my TSH test to be abnormal?
Abnormal TSH results can signal thyroid disorders, but they may also reflect other conditions like pituitary tumors, kidney disease, or medications. Your doctor will review your full medical history and other tests to determine the cause.
How often should I get a TSH test?
TSH testing frequency depends on your health status. If you have a thyroid condition, your doctor may recommend regular monitoring. Otherwise, tests are usually done only when symptoms or other signs suggest a thyroid issue.
Can lifestyle changes affect TSH levels?
Yes, diet (e.g., iodine intake), stress, sleep, and exercise can influence thyroid function indirectly. Avoiding excessive stress, eating a balanced diet, and getting enough sleep may support stable thyroid health, but TSH testing remains the best way to assess thyroid function.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy