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Thyroid-stimulating hormone (TSH) concentration in plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of thyroid-stimulating hormone (TSH) in your blood plasma. TSH is a hormone produced by your pituitary gland that helps regulate your thyroid function.

Quick summary

["TSH helps your thyroid produce hormones that control metabolism and energy levels."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
3018-9
Short code
Thyrotropin releasing horm Plas-mCnc
Synonyms
Thyrotropin releasing horm Plas-mCnc
Category
chemistry
Sample
plasma
Container
Lavender-top (EDTA) or Green-top (Heparin)
Units
N/A
Ref low
0.8
Ref high
1.2
Critical range
— – 5 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
85610
SNOMED
396252006
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may order this test to check for thyroid problems, such as hypothyroidism (when your thyroid doesn’t produce enough hormones) or hyperthyroidism (when it produces too much). It’s also used to monitor treatment for thyroid disorders or to screen for conditions like pituitary tumors.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for 8–12 hours before the test if it’s part of a more complex evaluation. Bring any medications you’re currently taking to your appointment.

What the Test Involves

A healthcare professional will draw blood from a vein in your arm. You may feel a slight pinch, but it typically doesn’t cause discomfort. The blood sample is then sent to a lab for analysis.

What the Results Mean

Results help determine whether your thyroid is functioning normally. Abnormal levels can signal underlying health issues that need further evaluation or treatment.

Reference range

INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A

Specimen: plasma

Inform your healthcare provider if you are taking blood thinners. No special preparation required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

TSH is a key marker for thyroid health. Low levels may indicate hyperthyroidism, while high levels often suggest hypothyroidism. It’s also useful for detecting early thyroid dysfunction before symptoms appear, such as fatigue, weight changes, or mood shifts.

Short name

TSH Plasma

Frequently asked questions

How often should I get this test?
The frequency depends on your health status. If you have a thyroid condition, your provider may recommend regular monitoring. Otherwise, it’s often ordered as needed for symptoms or diagnostic purposes.
What are typical reference ranges?
Reference ranges vary by lab and may differ slightly. Generally, TSH levels below 0.4 mIU/L may indicate hyperthyroidism, while levels above 4.0 mIU/L may suggest hypothyroidism. Your results should always be interpreted by your healthcare provider.
Can diet or medications affect TSH test results?
Yes, certain medications (like thyroid hormone drugs) or dietary factors (such as iodine intake) can influence TSH levels. Always inform your provider about all medications and supplements you take.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy