Tianeptine/Creatinine Ratio, Urine
A urine test that measures tianeptine relative to creatinine, helping assess drug exposure while accounting for differences in urine concentration.
["This test can help determine whether tianeptine is present in the urine and interpret its level relative to urine concentration."]
Key facts at a glance
- LOINC
- 101795-3
- Short code
- Tianeptine/Creat Ur Cfm
- Synonyms
- Tianeptine/Creat Ur Cfm
- Category
- kidney
- Sample
- urine
- Container
- Sterile urine container
- Units
- N/A
- Ref low
- 0.8
- Ref high
- 1.2
- Critical range
- — – 5 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- confirm
- CPT
- 85610
- SNOMED
- 396252006
- Specimen volume
- 10 mL
- Stability
- Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
What is this test?
This test measures the amount of tianeptine, an antidepressant medicine, in urine and compares it with the amount of creatinine in the same sample. Creatinine is a waste product commonly used to help account for how concentrated a urine sample is.
Why might I need this test?
A clinician may order this test to assess recent tianeptine exposure, monitor medication use, or evaluate concerns about adherence. It may also be used as part of a broader drug-testing program when use of tianeptine is uncertain.
How is the test performed?
A urine specimen is collected and analyzed in the laboratory to determine the tianeptine and creatinine amounts. The laboratory then reports the tianeptine-to-creatinine ratio.
How do I prepare for the test?
Follow the collection instructions provided by the laboratory or clinician. Tell the healthcare team about all medicines and supplements you take, and do not stop or change tianeptine or other medicines unless your clinician instructs you to do so.
Reference range
INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A
Inform your healthcare provider if you are taking blood thinners. No special preparation required.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
A detectable result generally indicates that tianeptine was present in the urine at the time of collection. A high or low ratio may reflect differences in medication dose, timing, urine concentration, kidney function, or individual metabolism, so results should be interpreted alongside the clinical history. The test alone cannot establish the exact dose taken, the time it was taken, or whether misuse occurred.
Short name
Urine tianeptine-to-creatinine ratio
Frequently asked questions
Does this test show how much tianeptine I am taking?
Why is creatinine included in the result?
Will this test detect other antidepressants or drugs?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy