Anti-Tissue Inhibitor of Metalloproteinase-1 (TIMP-1) Antibody (Serum) by Line Blot Assay
This test detects antibodies against Tissue Inhibitor of Metalloproteinase-1 (TIMP-1), a protein involved in regulating tissue repair and inflammation. It may be used to evaluate autoimmune conditions or immune-related disorders.
["This test helps identify certain immune system responses that may affect tissue health or inflammation over time."]
Key facts at a glance
- LOINC
- 88739-8
- Short code
- TIF1-gamma Ab Ser Line blot-aCnc
- Synonyms
- TIF1-gamma Ab Ser Line blot-aCnc
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- line-blot
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Might Be Ordered
Your healthcare provider may recommend this test if you have symptoms or conditions linked to autoimmune diseases, chronic inflammation, or unexplained tissue damage. It could also be part of a broader evaluation for conditions like systemic lupus erythematosus, rheumatoid arthritis, or other connective tissue disorders.
What to Expect Before the Test
No special preparation is needed for this test. You’ll provide a blood sample, usually drawn from your arm. The sample will be sent to a lab for antibody detection using a line blot assay, which identifies specific immune responses.
What the Results Mean
Results are qualitative (positive or negative) and indicate the presence or absence of TIMP-1 antibodies. A positive result suggests your immune system may be reacting to TIMP-1, which could be linked to an underlying autoimmune or inflammatory condition.
Common Conditions Monitored
This test is often used to support diagnosis or monitor conditions where TIMP-1 antibodies are suspected, such as certain autoimmune rheumatic diseases or vasculitis. It may also be part of research or specialized diagnostic protocols.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
TIMP-1 is a naturally occurring protein that helps control tissue breakdown and repair. Antibodies against TIMP-1 may indicate an abnormal immune response, potentially contributing to inflammation, fibrosis (scarring), or organ damage. While not all positive results mean a definitive diagnosis, they can guide further testing or treatment planning, especially in patients with suspected autoimmune disorders.
Short name
TIMP-1 Antibody Screening
Frequently asked questions
What does a positive result mean?
Could this test be used to diagnose a specific disease?
How often would I need this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy