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Tissue Inhibitor of Metalloproteinase-1 (TIMP-1) Antibody Screening by Line Blot

Published: August 9, 2026Updated: August 16, 2026

This test detects antibodies related to TIMP-1, a protein involved in tissue repair and inflammation. It may help identify autoimmune or inflammatory conditions.

Quick summary

["This screening checks for unusual immune responses linked to TIMP-1, which could signal underlying health concerns."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
82448-2
Short code
TIF1-gamma Ab Ser Ql Line blot
Synonyms
TIF1-gamma Ab Ser Ql Line blot
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
line-blot
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test uses a line blot method to screen for specific antibodies against TIMP-1, a protein that helps regulate tissue breakdown and repair. This may be part of an evaluation for autoimmune or inflammatory disorders.

Why It Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms or conditions linked to immune system dysfunction, such as chronic inflammation, connective tissue disorders, or unexplained fatigue.

Sample Collection and Process

A blood sample is typically collected from a vein in your arm. The sample is processed to separate serum or plasma, which is then analyzed using a line blot assay to detect TIMP-1 antibodies.

What to Expect Before the Test

No special preparation is usually needed, but inform your provider about any medications or conditions that could affect results. Avoid strenuous activity before the draw if advised.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated or abnormal antibody levels to TIMP-1 may suggest autoimmune activity, such as in conditions like systemic lupus erythematosus or other connective tissue diseases. Further testing may be needed to confirm diagnosis or guide treatment.

Short name

TIMP-1 Antibody Screening (Line Blot)

Frequently asked questions

What does a positive result mean?
A positive screening result indicates the presence of TIMP-1 antibodies, which may warrant additional diagnostic testing to explore potential autoimmune or inflammatory causes. Results alone do not diagnose a condition.
How long will I need to wait for results?
Results are typically available within 24 to 72 hours, depending on lab processing times. Your provider will discuss the findings with you during your follow-up visit.
Can lifestyle changes affect this test?
While lifestyle factors like diet or stress may influence overall health, they are unlikely to directly alter antibody levels detected in this test. Follow your provider’s guidance for any related recommendations.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy