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Tigecycline Susceptibility by Molecular Testing (Slow-Acting Mechanism)

Published: August 9, 2026Updated: August 16, 2026

This test checks how tigecycline, a broad-spectrum antibiotic, may affect certain bacteria in your sample. It helps determine if the bacteria are likely resistant or sensitive based on slow-acting mechanisms.

Quick summary

["This test helps guide antibiotic treatment by assessing bacterial response to tigecycline over time."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
55158-0
Short code
Tigecycline Islt SlowMyco
Synonyms
Tigecycline Islt SlowMyco
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
method-for-slow-growing-mycobacteria
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

Tigecycline is an antibiotic used to treat serious infections caused by bacteria that may not respond to other medications. This test evaluates the bacteria’s reaction to tigecycline by analyzing genetic or biochemical markers that indicate slow resistance mechanisms. The result helps clinicians decide if tigecycline is an appropriate choice for your infection.

Why It’s Done

Your healthcare provider may order this test if you have a bacterial infection that is difficult to treat with standard antibiotics. Slow-acting resistance mechanisms can sometimes be missed with traditional testing methods, so this test provides additional insight into how your bacteria might respond to tigecycline.

How the Test Works

This test involves collecting a sample (likely blood, urine, or other bodily fluid) and analyzing it using advanced molecular techniques. The slow mechanism detection identifies specific genetic or metabolic changes that suggest resistance patterns over time, rather than immediate resistance.

What to Expect Before the Test

No special preparation is typically required unless your provider specifies. Follow any instructions they give, such as fasting or avoiding certain medications, to ensure accurate results. Bring any recent medications or supplements to discuss with your provider.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Results from this test can influence treatment decisions by confirming or challenging the effectiveness of tigecycline. Slow-acting resistance may indicate that the bacteria are developing resistance gradually, which could require alternative antibiotics or prolonged treatment. Early detection helps prevent unnecessary antibiotic use and reduces the risk of antibiotic resistance in your community.

Short name

Tigecycline MIC Screening

Frequently asked questions

What does a positive or negative result mean?
A positive result suggests that the bacteria may be resistant to tigecycline through slow-acting mechanisms, meaning it might not be the best antibiotic choice for your infection. A negative result indicates that tigecycline is likely effective, but further testing may still be needed to confirm.
How long will it take to get the results?
Results from this molecular test are usually available within a few days to a week, depending on lab processing times. Your healthcare provider will contact you once the results are ready.
Can I take antibiotics before this test?
If your provider has ordered this test, avoid taking antibiotics unless instructed. Taking antibiotics before testing may interfere with the results and could delay appropriate treatment decisions.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy