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###1: TIMO-THY IgG Antibodies, Qualitative (Thyroid Microsomal and Thyroglobulin Antibodies)

Published: August 9, 2026Updated: August 16, 2026

###3: This test checks a blood sample for IgG antibodies directed against thyroid proteins, including thyroid peroxidase/microsomal antigens and thyroglobulin. It can help identify autoimmune thyroid disease when interpreted with thyroid function tests.

Quick summary

["###4: A positive result supports autoimmune thyroid disease, but thyroid function tests are needed to determine whether the thyroid is overactive, underactive, or still functioning normally."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
10953-8
Short code
Timothy IgG Qn
Synonyms
Timothy IgG Qn
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

###5: What the test measures

###6: TIMO-THY is a qualitative thyroid autoantibody test. It looks for IgG antibodies associated with immune attacks on the thyroid rather than measuring thyroid hormone levels directly.

###7: Why it is performed

###8: The test may be ordered when symptoms or laboratory results suggest Hashimoto thyroiditis, Graves disease, or another autoimmune thyroid condition. It is also sometimes used during the evaluation of thyroid enlargement or unexplained thyroid test abnormalities.

###9: How results are reported

###10: A qualitative result is generally reported as positive or negative. A positive result means the expected antibodies were detected, while a negative result means they were not detected at the laboratory's testing threshold.

###11: Other tests involved

###11: Thyroid autoantibody results are interpreted alongside tests such as thyroid-stimulating hormone and free thyroxine. These tests show how the thyroid is functioning and help distinguish among different thyroid disorders.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

###13: Clinical significance: A positive TIMO-THY result indicates thyroid autoimmunity and may support a diagnosis of Hashimoto thyroiditis or Graves disease, particularly when compatible symptoms and thyroid function abnormalities are present. However, thyroid antibodies can occasionally be present without current thyroid dysfunction, so a positive result does not by itself prove active disease. A negative result reduces the likelihood of some common autoimmune thyroid disorders but does not completely exclude them.

Short name

###2: Thyroid IgG antibody test, qualitative

Frequently asked questions

###14: Does a positive result mean I definitely have a thyroid disorder?
###15: No. It shows that thyroid-directed IgG antibodies are present, which supports thyroid autoimmunity. Your symptoms, medical history, and thyroid function tests are needed to determine whether you have an active thyroid disorder.
###16: Can someone with autoimmune thyroid disease have a negative result?
###17: Occasionally, yes. Antibody levels or testing methods may differ, and some autoimmune thyroid conditions do not produce the antibodies measured by this test. Clinical findings and thyroid function testing remain important.
###18: Does this test measure my thyroid hormone levels?
###19: No. TIMO-THY detects antibodies; it does not directly measure thyroid hormone levels. Tests such as thyroid-stimulating hormone and free thyroxine are used to assess thyroid function.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy