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Thyroglobulin (serum/plasma) with electrophoresis profile

Published: August 9, 2026Updated: August 17, 2026

This test measures thyroglobulin levels in your blood and analyzes their pattern using electrophoresis, often used to monitor thyroid cancer treatment.

Quick summary

["Helps track thyroid cancer treatment progress by checking protein levels and their movement through blood components."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
103007-1
Short code
Timothy (rPhl p) 5 IgE RAST
Synonyms
Timothy (rPhl p) 5 IgE RAST
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
10
Ref high
40
Critical range
— – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
rast
CPT
84484
SNOMED
302774002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may order this test if you have a history of thyroid cancer, especially after treatment like surgery or radioactive iodine therapy. It helps ensure the cancer hasn’t returned or spread. This test is also used in follow-up care to monitor long-term effects of treatment.

What to Expect Before the Test

No special preparation is usually needed. You may have a small needle inserted into your arm or hand to draw blood. If you’re on blood thinners, let your doctor know before the test.

What the Test Results Mean

Thyroglobulin levels can vary. Low levels may indicate successful treatment, while higher levels could signal recurrence or thyroid issues. The electrophoresis part helps identify abnormal protein patterns that might suggest cancer activity.

Common Causes of Abnormal Results

Elevated levels can occur if cancer has returned, thyroiditis (inflammation), or other thyroid disorders. Low levels might mean the body is producing less protein normally. Always discuss results with your healthcare provider.

Reference range

Adult: 10-40 U/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Thyroglobulin (Tg) profile

Frequently asked questions

What symptoms might this test help diagnose?
This test primarily helps track thyroid cancer progression or treatment response rather than diagnosing symptoms directly. Symptoms like fatigue, weight changes, or unexplained swelling may prompt further evaluation, including this test.
How often should I get this test?
Your doctor will determine the frequency based on your medical history and treatment plan. Follow-up tests may occur every few months to years, depending on your situation.
Can diet or medications affect this test?
Some medications (like thyroid hormone replacements) or certain foods may influence thyroid function indirectly. Always inform your doctor about all medications or supplements you take before testing.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy