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Platelet Function Analyzer (PFA-100) Platelet Aggregation Inhibition Test with Tirofiban

Published: August 9, 2026Updated: August 16, 2026

This test measures how well your platelets function in the presence of the medication tirofiban, which helps prevent blood clots. It’s often used to assess bleeding risks in patients on antiplatelet drugs.

Quick summary

["This test helps doctors check if tirofiban is working properly to prevent dangerous blood clots."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
73116-6
Short code
Tirofiban ind plt IgM SerPl Ql FC
Synonyms
Tirofiban ind plt IgM SerPl Ql FC
Category
hematology
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
flow-cytometry
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Doctors may order this test if you’re taking tirofiban (a medication like Plavix) and have concerns about bleeding risks, especially before surgery or other procedures. It helps ensure the medication is working as intended to keep your blood from clotting too easily.

What to Expect Before the Test

No special preparation is needed, but you may be asked to stop certain medications (like aspirin) for a short time before the test, depending on your doctor’s instructions. Bring your medication list to the lab.

What Happens During the Test

A small sample of your blood is taken using a needle. The blood flows through a special device that measures how long it takes for platelets to form clots under tirofiban’s influence. This helps assess platelet function.

What the Results Mean

Results are compared to a standard range to see if your platelets are responding normally to tirofiban. Abnormal results may indicate the medication isn’t working well or that you’re at higher risk for bleeding.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Tirofiban Platelet Function Test

Frequently asked questions

Why might my doctor want this test?
Your doctor may order this test if you’re on tirofiban to prevent blood clots, especially before surgery, dental work, or if you have a history of bleeding problems. It helps balance the risk of clots versus bleeding risks.
What does a high or low result mean?
A high result might suggest tirofiban isn’t working well, while a low result could mean your platelets are more likely to clot. Your doctor will discuss these findings with you based on your overall health.
Can I eat or drink before this test?
You can eat and drink normally unless your doctor specifies otherwise. Avoid alcohol or certain medications (like aspirin) for a few days before the test, as they can affect blood clotting.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy