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Tobramycin in Serum or Plasma (Mass Concentration)

Published: August 9, 2026Updated: August 17, 2026

This test measures the amount of the antibiotic tobramycin in your blood, typically taken to monitor levels when you're receiving this medication.

Quick summary

["Tobramycin levels help ensure safe dosing and avoid potential side effects."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
35670-9
Short code
Tobramycin SerPl-mCnc
Synonyms
Tobramycin SerPl-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0
Ref high
17
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you’re receiving tobramycin, a strong antibiotic used to treat serious bacterial infections like pneumonia, sepsis, or infections in the bloodstream, lungs, or bones. It helps track how much of the drug is in your blood to prevent toxic levels that could harm your kidneys or nerves.

What to Expect Before the Test

No special preparation is needed. A blood sample is drawn from a vein, usually in your arm, by a healthcare professional. The process is quick and typically painless, though you might feel a slight pinch. You can resume normal activities immediately afterward.

What the Test Results Mean

Results are compared to a reference range specific to tobramycin, which varies based on your weight, kidney function, and how you’re being treated. High levels may indicate too much drug in your system, while low levels could mean the infection isn’t fully responding to treatment.

Potential Side Effects or Risks

Tobramycin can cause side effects like nausea, vomiting, or kidney damage if levels are too high. Your provider will adjust your dose if needed based on these results. Rarely, it may affect your nerves or hearing.

Reference range

NCBI: NSE 0-17 ng/mLN/A

Specimen: serum

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Monitoring tobramycin levels is critical for patients with kidney problems or those receiving high doses. It ensures the antibiotic remains effective while minimizing harm. Abnormal results prompt dose adjustments or alternative treatments.

Short name

Tobramycin Level

Frequently asked questions

How long does it take to get my results?
Results are usually available within 24 to 48 hours, depending on your lab’s processing time. Your healthcare provider will discuss them with you during your follow-up visit.
Can I eat or drink before this test?
You can eat and drink normally before the test unless instructed otherwise by your provider. No fasting is required.
What if my levels are too high?
If levels are too high, your doctor may reduce your dose, switch to a different antibiotic, or adjust your treatment plan to protect your kidneys and nerves while still fighting the infection.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy