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Tocopherol (Vitamin E) and Cholesterol, Serum/Plasma

Published: August 9, 2026Updated: August 17, 2026

Measures vitamin E (tocopherol) and cholesterol in blood to help assess vitamin status and cardiovascular risk factors.

Quick summary

["This test can help identify vitamin E deficiency or imbalance and evaluate blood cholesterol levels."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
59250-1
Short code
Tocopherols/Cholest SerPl-sRto
Synonyms
Tocopherols/Cholest SerPl-sRto
Category
lipid
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
5
Ref high
20
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This blood test measures tocopherol, also known as vitamin E, along with total cholesterol. Vitamin E is a fat-soluble antioxidant that helps protect cells from oxidative damage, while cholesterol is a substance used by the body to build cells and hormones.

Why might I need this test?

A clinician may order this test to assess vitamin E status, particularly in someone with malnutrition, a condition that affects fat absorption, or symptoms that could be related to a vitamin deficiency. Cholesterol may be included as part of an evaluation of cardiovascular risk or the effectiveness of lipid-lowering treatment.

How is the test performed?

A blood sample is collected from a vein and sent to a laboratory for analysis. The laboratory measures the amount of vitamin E and cholesterol in the serum or plasma portion of the blood.

How do I prepare for the test?

No special preparation is usually required for vitamin E measurement. If the test is being used to evaluate cholesterol, your clinician may ask you to fast for several hours beforehand; follow any fasting instructions provided with the test order.

Reference range

NCBI: Vitamin E 5-20 µg/mLN/A

Specimen: serum

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

A low vitamin E level may occur with inadequate intake, impaired fat absorption, or certain medical conditions, although symptoms are not specific to vitamin E deficiency. High or low cholesterol can influence cardiovascular risk assessment, and results should be interpreted alongside diet, medical history, and other lipid measurements.

Short name

Vitamin E and Cholesterol

Frequently asked questions

Does this test show whether I have a vitamin E deficiency?
It can help assess vitamin E status, but the result must be interpreted with your symptoms, medical history, and other nutritional tests. A low level can be associated with poor intake or problems absorbing dietary fat.
Is this the same as a standard cholesterol panel?
Not necessarily. It measures total cholesterol along with vitamin E and is not a complete substitute for a standard lipid panel, which usually includes several additional cholesterol measurements.
Do I need to fast before this test?
Fasting may be recommended if cholesterol is being evaluated, while vitamin E measurement generally does not require fasting. Confirm the preparation instructions with your healthcare provider or testing laboratory.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy