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Total IgE (Immunoglobulin E) Level

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of Immunoglobulin E (IgE) in your blood. IgE is a type of antibody that plays a role in allergic reactions and responses to certain parasites.

Quick summary

["IgE levels help identify allergies or immune responses to allergens."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
40841-9
Short code
Tomato IgE/IgE total %
Synonyms
Tomato IgE/IgE total %
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is Immunoglobulin E (IgE)?

IgE is a protein produced by your immune system in response to allergens like pollen, dust, or certain foods. While it’s normally present in small amounts, higher levels may signal an allergic reaction or an overactive immune response.

Why Might You Need This Test?

Your doctor may order this test if you have symptoms like sneezing, itching, hives, or asthma, or if you suspect an allergy to specific triggers. It can also help diagnose conditions like allergic rhinitis, eczema, or parasitic infections.

How Is the Test Performed?

A small blood sample is drawn from a vein in your arm. The sample is then sent to a lab for analysis using an immunoassay method to measure IgE levels.

What Do My Results Mean?

Results are typically reported in units of IgE per milliliter (IU/mL). Higher than normal levels may indicate allergies, asthma, or other immune-related conditions. Your doctor will interpret results in the context of your symptoms and medical history.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

IgE Total

Frequently asked questions

What causes elevated IgE levels?
Elevated IgE levels are often linked to allergies, asthma, or chronic inflammatory conditions. They may also appear in response to parasitic infections or certain autoimmune disorders. Your doctor will consider your symptoms and medical background to determine the cause.
Can IgE levels ever be low?
Yes, IgE levels can be low in some cases, such as in people with certain immune deficiencies or those who have had severe allergic reactions in the past. Low IgE is less commonly associated with clinical concerns but may warrant further evaluation if symptoms persist.
How often should I get this test?
The frequency of this test depends on your symptoms and medical needs. Your doctor may recommend retesting if your condition changes, such as worsening allergies or new symptoms. Follow-up may also be needed if you’re being treated for an allergy or related condition.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy