Skip to content

Serum or Plasma Total Protein with Albumin/Globulin Ratio (Protein Electrophoresis Profile)

Published: August 9, 2026Updated: August 16, 2026

This test measures the distribution of proteins in your blood, including albumin and globulins, to help identify potential protein abnormalities.

Quick summary

["Assesses protein balance and may reveal conditions affecting blood protein composition."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
102088-2
Short code
Torch IgG pnl Ser
Synonyms
Torch IgG pnl Ser
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Proteins Are Measured?

Electrophoresis separates blood proteins into different fractions based on size and charge. Albumin, globulins (including immunoglobulins), and other proteins are analyzed. This helps distinguish between normal and abnormal protein patterns.

Why Is This Test Done?

Your doctor may order this test to investigate symptoms like fatigue, swelling, or unexplained weight changes. It can also help diagnose conditions such as liver disease, kidney problems, or certain cancers (e.g., multiple myeloma).

Common Conditions Affecting Protein Levels

Abnormal results may indicate conditions like chronic kidney disease, liver disease, malnutrition, or autoimmune disorders. Low albumin could signal fluid retention or protein loss, while high globulins might suggest inflammation or immune system issues.

Sample Preparation and Testing Process

Blood is drawn and processed into serum or plasma. Proteins are separated using electrophoresis, and results are compared to standard patterns to identify any deviations.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Protein Electrophoresis Profile

Frequently asked questions

What does a protein electrophoresis profile tell me about my health?
It shows the balance of different proteins in your blood, which can reveal whether your body is producing too much or too little of certain proteins. This may point to conditions like liver or kidney disease, infections, or immune disorders.
How long does it take to get results from this test?
Results are typically available within 24 to 48 hours, depending on your lab’s processing time. Follow-up with your healthcare provider to discuss findings.
Can diet affect protein electrophoresis results?
Dietary changes that significantly alter protein intake (e.g., extreme protein restriction or high-protein diets) may impact results. However, standard protein electrophoresis focuses on intrinsic protein patterns rather than acute dietary shifts.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy