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Total Protein with Albumin and Globulin Profile (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures your total protein levels in your blood, along with the amounts of albumin and globulin proteins. These proteins help maintain fluid balance, support immunity, and transport nutrients.

Quick summary

["Understanding your protein balance can help identify issues like malnutrition, liver disease, or immune disorders."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
50689-9
Short code
T palldm Ab CSF Ql HA
Synonyms
T palldm Ab CSF Ql HA
Category
chemistry
Sample
csf
Container
Sterile tube
Units
N/A
Ref low
1.5
Ref high
9
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ha
CPT
83002
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

What Does This Test Measure?

Your blood sample is analyzed to determine three key components: total protein, albumin, and globulin. Total protein is the sum of all proteins in your serum or plasma. Albumin is the most abundant protein, responsible for keeping fluids within your blood vessels. Globulins include proteins like antibodies and transport proteins that support immunity and other functions.

Why Is This Test Important?

Measuring these proteins helps doctors assess your overall health, especially if you have symptoms like swelling, frequent infections, or unexplained weight changes. It can also help diagnose conditions like liver disease, kidney problems, or malnutrition.

How Is the Test Performed?

A small blood sample is drawn from a vein in your arm. The sample is then sent to a lab where it is processed to separate and measure the protein components. The results are compared to standard reference ranges to identify any abnormalities.

What Are Common Causes of Abnormal Results?

Low levels of total protein, albumin, or globulins may indicate conditions such as liver disease, kidney disease, malnutrition, or severe infections. High levels might suggest conditions like multiple myeloma (a blood cancer) or dehydration.

Reference range

Follicular: 1.5-9.0 mIU/mLN/A

Specimen: csf

For females: inform if menstrual cycle status. For certain tests, timing within menstrual cycle may matter.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Protein Breakdown Test

Frequently asked questions

How long does it take to get results from this test?
Results from this test are typically available within 1 to 3 business days, depending on your lab’s processing time. Your healthcare provider will discuss the results with you during your follow-up visit.
What should I do if my protein levels are outside the normal range?
If your test results show abnormal protein levels, your doctor may recommend additional tests or treatments to address the underlying cause. This could include dietary changes, medications, or further diagnostic procedures to identify the exact issue.
Can diet affect the results of this protein test?
Yes, diet can influence protein levels. High-protein diets or certain medical conditions (like kidney disease) may temporarily alter results. It’s best to follow your doctor’s advice regarding dietary restrictions before or after the test if needed.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy